What is the specific pathological classification of lupus nephritis? This is a technical term, I hope my friends at school can understand it, and I hope the following nephrologists can help you: the unification of pathological classification is of great significance for guiding clinical individualized treatment and judging prognosis. The classification of lupus nephritis (LN) was first proposed by WHO in 1974, first revised in 1980 and revised again in 1995. In 2003, the International Society of Nephrology and the Society of Renal Pathology (ISN/RPS) revised the classification standard of LN for the third time. LN classification standard in 2003 divided LN into six types. Type ⅰ is mild pathological LN in mesangium: it is basically normal under light microscope, and immune complex deposition in mesangium can be seen by immunofluorescence. Type ⅱ is mesangial proliferative LN: mesangial cells proliferate or mesangial matrix increases under light microscope, accompanied by immune complex deposition in mesangial area, and a small amount of isolated subepithelial or subepithelial deposition can be seen under immunofluorescence or electron microscope. Type ⅲ is focal LN: the glomeruli involved are less than 50% of all glomeruli, which can be characterized by active or inactive lesions, focal, segmental or spherical lesions, and proliferative lesions inside or outside capillaries. Type ⅲ (A) is an active lesion with focal proliferative lymph nodes; Type ⅲ (type A C) is an active chronic disease with focal proliferative sclerosing nephritis. Type Ⅲ (C) is a chronic disease with focal sclerosing nephritis. Type Ⅳ is diffuse LN: the involved glomeruli account for more than 50% of all glomeruli, and typical cases often have diffuse deposition of immune complexes under the skin, with or without mesangial lesions. According to glomerular lesions, it can be divided into diffuse segmental LN (involving glomeruli with segmental lesions) and diffuse spherical LN (involving glomeruli with spherical lesions). Ⅳ s (a) is active segmental hyperplasia, Ⅳ g (a) is active spherical hyperplasia, Ⅳ s (AC) is active chronic segmental hyperplasia and sclerosis, Ⅳ g (a c) is active chronic spherical hyperplasia and sclerosis, Ⅳ s (c) is chronic segmental sclerosis and Ⅳ g (c) is chronic spherical sclerosis. Type ⅴ is membranous LN: under the light microscope, the deposition of immune complex under the epidermis can be seen, with or without mesangial lesions. Immunofluorescence or electron microscopy showed that spherical or segmental continuous immune complexes were deposited, and type V often coexisted with type III or V. Type ⅵ is progressive sclerosis LN: greater than LN:90% glomerulus is spherical sclerosis. Active lesions refer to the following conditions: cell proliferation, nuclear fragmentation, cellulose-like necrosis, glomerular basement membrane destruction, cell or fiber crescent formation, platinum ear and so on. Chronic diseases refer to segmental or global glomerulosclerosis, fibrous adhesion and fibrous crescent formation. Through the introduction of the above experts, I believe you have a certain understanding of the pathological classification of lupus nephritis, hoping to help you. Recommended reading: Changchun Eye Hospital specializes in condyloma acuminatum, Beijing Epilepsy Hospital, Shanghai Vitiligo Treatment, which hospital in Beijing has the best painless abortion, and the Beauty Department of Guangzhou Yueyang First Hospital. Does it hurt to do painless abortion surgery? Xi 'an Most Assured Condyloma Acuminatum Hospital, Tangshan Huadu Plastic Surgery, Hebei.