Patients often have a heavy mental burden, such as insecurity, and can cause headaches, dizziness, fear of vibration and other syndromes. The longer the duration of skull defect, the higher the incidence of skull defect syndrome and secondary brain injury. In order to restore the tightness of cranial cavity, keep the physiological intracranial pressure stable and relieve skull defect syndrome. Skull repair should be performed if the diameter of skull defect exceeds 3 cm, there is no muscle coverage and no contraindications. It is generally believed that 3~ 6 months after craniotomy is suitable for repair; Children can have plastic surgery after they are 3 to 5 years old.

All patients had no contraindications to surgery, and all of them were examined by head CT and forehead X-ray. In the digital shaping group, 2mm thick thin-slice CT scanning was performed routinely, and the frontal bone was reconstructed in three dimensions. Then, the two-dimensional titanium mesh is molded by a "titanium mesh digital molding machine" to manufacture a two-dimensional personalized titanium mesh prosthesis that is completely consistent with the patient's frontal bone defect, and sterilized for later use. In the three-dimensional plastic group, a three-dimensional plastic titanium mesh which is more than 2cm larger than the edge of the defect was used, preformed with a traditional mold and sterilized for later use.