For a long time, people have always thought that cytoskeleton is only a unique structure of eukaryotes, but recent studies have found that it also exists in prokaryotes such as bacteria. So far, FtsZ, MreB and CreS found in bacteria are similar to tubulin, actin filament and intermediate filament in eukaryotic cytoskeleton proteins in turn. FtsZ can assemble at the cell division site to form Z-ring structure, and participate in the regulation of cell division through this structure; MreB can form spiral filament structure, and its main function is to maintain cell morphology and regulate chromosome segregation. CreS exists in Corynebacterium crescentum, forming a curved or spiral filamentous structure under the concave cell membrane, which plays an important role in maintaining the morphology of Corynebacterium crescentum cells.