This film is adapted from the works of French novelist Thierry Jonquet. A plastic surgeon (antonio banderas) discovers that his daughter has been raped unfortunately, and his angry and sad father will take soul-stirring revenge on the criminals who hurt his daughter.

In the film, banderas plays Legard, a famous plastic surgeon, but it is different from the plot of revenge for his daughter in previous reports. In the official synopsis released by the latest production company, Legard's wife was burned to death in a traffic accident, which gave him the idea of creating a "skin" that could save her at that time. For 12 years, Legard used stem cell technology and transgene between human and animals to carry out his research. However, just "breaking the moral taboo" in the laboratory is not the whole of his crime. Amodova's 18 works once again cooperated with banderas, and it has been 20 years since their last film "Tie Me Up, Tie Me Up". The film was inspired by the French novelist Thierry Jonquet's Tarantula, but it is quite different from the original. This is the first time that Amodova has tried a horror theme. He once said that this movie is "a horror movie without screaming and scaring", "It won't follow any rules" and "It will be the cruelest movie I have ever made, and the role of banderas is extremely cruel.