major constituent
First year
1934, Meyer, a professor of ophthalmology at Columbia University in the United States, first isolated the substance from bovine vitreous. Hyaluronic acid, with its unique molecular structure and physical and chemical properties, has many important physiological functions in vivo, such as lubricating joints, regulating the permeability of blood vessel walls, regulating the diffusion and operation of protein, water and electrolytes, and promoting wound healing. More importantly, hyaluronic acid has a special water retention function and is the best moisturizing substance found in nature at present. It is called an ideal natural moisturizing factor (NMF, for example, 2% pure hyaluronic acid aqueous solution can firmly maintain 98% moisture. Hyaluronic acid is a multifunctional matrix, and hyaluronic acid (HA) is widely distributed in all parts of human body. Skin also contains a lot of hyaluronic acid. The maturation and aging process of human skin also changes with the content and metabolism of hyaluronic acid. Hyaluronic acid can improve the nutritional metabolism of skin, make skin soft, smooth and wrinkle-free, increase elasticity, prevent aging, and is a good transdermal absorption promoter while moisturizing. Combined with other nutrients, it can play an ideal role in promoting nutrient absorption.
Main applications
Biochemical drugs has high clinical value and is widely used in various ophthalmic operations, such as intraocular lens implantation, corneal transplantation and anti-glaucoma surgery. It can also be used to treat arthritis and accelerate wound healing. When used in cosmetics, it can play a unique role in skin care, keep skin moist, smooth, delicate, tender and elastic, and has the functions of anti-wrinkle, beauty care and recovery of skin physiological functions. It is also a product of hyaluronic acid, because of the differences in raw material sources and manufacturing processes, the effect is obvious. The concentration of the product can't be used as a reference for product selection, but the purity, molecular weight and 3D structure will directly affect the water absorption effect of hyaluronic acid. Generally, the larger the molecular weight, the more complete the network structure, and the best water absorption effect will be achieved. Skin care products and cosmetics are very popular in the market, but hyaluronic acid made by many manufacturers is cheap. However, it may not be effective. Even oral hyaluronic acid promoted by some people will be decomposed into small unit molecules of sugars and amino acids after being absorbed by the stomach, and it must be produced in skin and connective tissue through self-synthesis, and its effect will inevitably be discounted.
Skin care and precautions
First year
Moisturizing and sealing are the dual missions of skin care. Truly high-quality hyaluronic acid must be an organic combination of macromolecular and micromolecule hyaluronic acid. Macromolecule hyaluronic acid (tens of thousands to hundreds of thousands of daltons) cannot penetrate the skin, but it can form a breathable film on the skin surface, making the skin smooth and moist, blocking the invasion of foreign bacteria, dust and ultraviolet rays, and protecting the skin from infringement. Low molecular weight hyaluronic acid (nano-hyaluronic acid HA 800 with molecular weight as low as 1000, OCO can easily penetrate the skin) has the functions of anti-inflammation, inhibiting the generation of germs and keeping the skin smooth. Can penetrate into the skin, synthesize skin endogenous macromolecular hyaluronic acid, and achieve the function of water retention; Provide a suitable place for cell proliferation and differentiation, and directly promote cell growth, differentiation, reconstruction and repair.
It is not suitable to inject when the joint inflammation is obvious, and then inject hyaluronic acid gel after the inflammation is eliminated.
When joint effusion occurs, the leakage of hyaluronic acid gel outside the joint cavity will cause pain, so it must be injected into the joint cavity.
Sometimes it will cause pain, and it will be quietly treated locally after injection of hyaluronic acid gel.
Hyaluronic acid will precipitate when it meets disinfectants such as benzalkonium chloride and quaternary ammonium salt. , so we should pay full attention to it when using it.
Pregnant women and lactating women should use it with caution, those with impaired liver function should use it with caution, and those who are allergic to hyaluronic acid gel should use it with caution.
So let's go to a guaranteed medical beauty institution for hyaluronic acid injection. I wish everyone more and more beautiful.
Jingmei plastic surgery