Precautions before autologous fat transplantation
(1) avoid menstruation as much as possible;
(2) No history of oral anticoagulants within half a month;
(3) There is no infection in the operation area (liposuction area);
(4) Preoperative oral administration of (human-like peptide) 10 ~ 20 days, twice a day, to store nutrition for the survival of newly transplanted fat particles.
(5) Patients with simple mastectomy need 3 years after operation;
(6) Take a bath before operation to clean the skin. Blood transfusion was performed 3 days after operation to keep the dressing dry.
Matters needing attention after autologous fat transplantation
Your own fat cells grow in different places, which is equivalent to a second rebirth. After fat filling, a large number of capillaries need to be generated around the transplanted fat cells. Each fat cell is an independent life, and each fat particle needs fresh blood to maintain its life. Using human-like peptide technology to stabilize and accelerate the reorganization of collagen fiber and capillary structure, so as to protect the tissue damage after autologous fat transplantation, realize the survival and stability of fat and avoid displacement.
(1) Three months after operation, oral (human-like peptide) was given twice a day to help the newly transplanted fat particles survive.
(2) Not doing a lot of fat metabolism exercise, dieting or taking fat-reducing drugs for three months after operation will lead to excessive fat consumption.
(3) Within 7 days after operation, try to avoid the water on the surgical site and ensure that the wound is clean and dry.
(4) It is forbidden to apply ice or hot compress after operation. Adipocytes are fragile after fat filling and prone to apoptosis under cold and hot stimulation.
(5) Rest quietly, and don't press the wound when sleeping, causing swelling.
How long does the survival rate and effect of autologous fat transplantation last? Is it permanent?
Studies have shown that the blood supply of transplanted adipose tissue, the number and recipient area of transplanted adipose tissue, the general nutritional status, the source of donors, the injection method of adipose tissue, the way of liposuction, the control of negative pressure during aspiration, the speed of centrifugal purification of adipose tissue, the dosage of growth factors, postoperative care and postoperative nutrition can all affect the survival rate of adipose tissue.
The problem of low survival rate: as long as fat survives, the effect is long-term, and the key is whether the natural metabolism process of fat and cell regeneration can be smooth. Fat filling depends on the activity of capillaries, so the formation of capillaries comes from the technology of "human-like peptide" transferring nutrients to newly transplanted fat cells, activating the channels between fat cells and making nutrients transfer to each other. The survival rate of autologous fat transplantation is about 80%. If there is insufficient nutrition, the newly transplanted adipose tissue will starve to death.
Effect of autologous fat filling
Three elements of autologous fat filling effect: fat transplantation survival! Stay alive! Stay alive!
The success of fat transplantation needs to go through the process of fat particle screening, transplantation, survival and metabolic renewal. After these processes are completed, the transplanted fat particles will be endless and accompany forever.
Process 1: When filtering fat, some damaged fat particles will be destroyed, and the damaged fat globules need maintenance. Irreparable transplanted particles will liquefy and eventually be digested by the body. If there is a large amount of liquefaction, you should go to the hospital for puncture and drainage, or negative pressure drainage.
Process 2: Transplantation. If the damaged fat globules are not adequately nourished, the damaged fat cells will be liquefied and eventually digested by the body, and new cells will be produced and capillaries will be stimulated by technology to prevent fat liquefaction.
Process 3: Blood transports nutrients to newly transplanted fat cells, activates the channels between fat cells and transports nutrients to each other. The activity of capillaries determines that cells enter periodic metabolism.
The advantages of this are:
A month can restore nature, and a month can basically reduce swelling, but it may take three months to completely restore nature.
First, within 24 hours after surgery, fat cells first encounter necrosis. After fat transplantation into the recipient area, in addition to the adipose tissue damage caused by fat extraction, normal fat particles will also be rapidly reduced due to the oxygen partial pressure of the graft. If the environment is not activated, it will directly lead to the necrosis of fat cells.
2. At 1-3 months after operation, necrosis caused the aggregation of inflammatory cells and macrophages, and the procedure of removing lipid droplets began. Macrophages devour necrotic adipocytes and other cells, and at the same time, they devour and digest some free lipid droplets between tissues. At this point, the swollen part filled with injected fat will gradually shrink. At the same time, the process of tissue repair has also begun. Surviving mesenchymal stem cells, mesenchymal stem cells in the recipient area and a small number of pluripotent stem cells that may be transferred from bone marrow will participate in tissue repair, microvascular reconstruction and recanalization, and restart fat regeneration.
Third, postoperative calcification appeared 6 months after transplantation, and it became worse with time. The reason of calcification after fat necrosis is that fatty acids decomposed after fat necrosis combine with calcium to form calcium soap, and fatty acids in calcium soap are replaced by phosphate and carbonate in blood to form calcium phosphate and calcium carbonate, which are deposited in tissues.
4. 9 months after operation, the clearance and repair were slow and limited. After the fibrocyst is completely formed, the process of clearance and regeneration almost stops, and the wrapping range of necrotic tissue is determined. The surviving adipose tissue has experienced a complete cell metabolism cycle, and will participate in the normal renewal and metabolism of the human body like other adipose tissues, maintaining long-term effects.
The survival rate of autologous fat transplantation has been improved with the continuous improvement of technical level in recent years, and its survival rate is as high as 80% at present.
Operation time of fat transplantation
The exposure time of extracted fat in vitro should be shortened as much as possible, because the fat in vitro is too long, and then injected into the body will die because of long-term lack of blood nutrition.
The operation time should be short, about 40 minutes to complete, the operation is rapid, the fat cells stay in vitro for a short time, and the polyfat cells are active; Simple and convenient operation. After the fluid dynamic fat extractor is connected, the swelling liquid injection, fat suction and fat collection are integrated, which avoids the complicated procedures such as injecting swelling liquid first and connecting negative pressure suction in the traditional method.