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Why does the toe that the sun can't shine grow melanoma?
Melanoma is caused by local abnormal skin pigment. What is a mole? Nevus are localized skin pigment abnormalities, which can occur at birth or the day after tomorrow. Healthy people can usually find 15 ~ 20 moles on the skin. Most of these moles are benign and do not need treatment. But there are some moles on the face, which affect the appearance and can be removed in different ways. There are several commonly used methods to remove moles: laser method, freezing method, electrocautery method, spot scanning method and chemical agent method. Black spot nevus is a kind of pigmented nevus, which often attracts special attention because of its local blackening, rough skin and long hard and short hair. Attention should be paid to moles that occur in parts of the body that are vulnerable to friction or injury, such as rapid growth and increase of the body, fading or deepening of the color, shedding of short hairs on the mole, redness around the mole, faintly visible bloodshot, festering and scabbing on the surface, and even forming lasting ulcers. Nearby lymph node enlargement, or some small satellite-like nevus around the big nevus, all indicate that the nevus has a tendency to malignant transformation. You should go to the hospital to ask a dermatologist and a surgeon for diagnosis, so as to deal with it in time. For the treatment of black spot nevus, small nevus with a diameter less than 0.5 cm can be cauterized by laser or high frequency electrotome. Its advantages are simple operation, less damage to normal tissues and less scar after healing. The disadvantage is that it is difficult to take the nevus tissue for pathological examination and it is not easy to remove it. There are also freezing and chemical etching to remove moles, because the impurities left behind stimulate the malignant transformation of nevus cells, which is not suitable. Resection of pigmented nevus by trephine can make up for the above shortcomings. After local skin anesthesia, the whole pigmented nevus is drilled with a trephine 0.2 cm larger than the diameter of the nevus, and the incision can be sutured with fine thread. Because the long axis of the incision is consistent with the skin lines or expression lines, the postoperative scar is not obvious and the cosmetic effect is good. What kind of mole should be removed? Dr. Li pointed out that in addition to aesthetic factors, in order to avoid becoming malignant melanoma, the following kinds of moles should be removed: 1 Moles that will be stimulated by long-term friction, such as those on bras and waist. 2. Nevus with atypical changes. Nevus with atypical appearance may become malignant, such as very dark nevus, uneven (mottled) pigment, uneven or irregular edge, unclear boundary, asymmetric left and right, and statistically larger than 5 mm in diameter. 3. A mole will change suddenly and rapidly. If the mole of the whole body changes at the same time because of the change of the black door, there is no doubt about it. If a single mole changes suddenly and rapidly, it is worth noting. 4. moles that grow in special parts. For example, moles growing on limbs (hands and feet) must be observed, because moles in these places are more likely to become malignant melanoma than moles in other places. 5. Mucosal nevus. Moles appeared in oral mucosa, conjunctiva, vagina and foreskin. 6. Nail groove nevus. The nail groove is connected with the skin under the nail, which may grow under the nail and be blocked by the nail, so it is not easy to see the change, and it grows at the end and is more likely to become malignant in the future. 7. Some moles are high-risk moles. The moles that babies can see at birth are called congenital moles, and there are not many congenital moles. According to statistics, 1% of newborns have moles. Not all congenital moles are inherently dangerous, and size is an important factor. Generally speaking, the bigger the mole, the greater the possibility of malignant transformation in the future, so the doctor suggested to remove it as soon as possible. Dangerous Malignant Melanoma Ou, a plastic surgeon at Taipei MacKay Hospital, said that a benign nevus will turn into malignant melanoma due to prominent melanin, extreme, itching, pain, bleeding and ulcer. Skin cancer mainly includes three types: malignant melanoma, basal cell carcinoma and squamous cell carcinoma. Malignant melanoma accounts for 4% of all skin cancers, but it leads to nearly 80% of skin cancer mortality, which is one of the worst prognosis of all cancers. 10 ~ 15% patients with malignant melanoma have a family genetic history. The incidence of malignant melanoma in yellow race is lower than that in white race. It is pointed out that 70 ~ 80% of malignant melanoma in China is acromegaly nevus, which is characterized by its predilection in palm, sole and other parts that may not be exposed to sunlight, as well as in body mucosa. Malignant melanoma of acromegaly often invades the skin basement membrane vertically and invades subcutaneous blood vessels or lymphatic vessels when the tumor is still very young, and then metastasizes. Once metastasized, the prognosis is extremely poor, and the three-year survival rate is only about 10%. Nevus may change, some changes are warning signals, they will become malignant, and some changes are benign. Whether the nevus is malignant or not can be determined by biopsy. In fact, the mole on the foot should be closely observed, because the probability of long-term friction becoming malignant melanoma is very high, and he has seen more than 10 cases of this situation. Not long ago, he removed a mole on the soles of the feet for an 85-year-old man and turned it into malignant melanoma. That mole should have been with the old gentleman for decades, and it has recently become malignant. "Once a mole becomes malignant melanoma, it will deteriorate rapidly," O 'Yun Sheng said. He's seen this before. The youngest is a 40-year-old mother with a mole of 0.5 cm on the knuckle side of her little toe, which has become malignant melanoma by biopsy. He advised her to have an operation at once and cut off the whole little toe, but the patient hesitated and dragged on for a month before coming back to the hospital to cut off the little toe. Half a year later, her cancer cells metastasized to the groin, spread to the whole body in a year or so, and died. Obviously, in the short period of one month that she hesitated, the cancer cells had metastasized. "The mole on the foot often rubs shoes, which makes it easier to turn from benign to malignant. If there are moles on the toes and soles of the feet, it is better to remove them as soon as possible. The prognosis of benign melanoma is good after complete resection. But once it is evaluated as malignant, even surgery can't cure it, because 30~70% of cases will metastasize. It has been reported that small malignant melanoma can survive for 12 months after resection, but the mortality rate within 2 years is 54%. If the malignant melanoma is resected in a large area, it can survive for 4 months, but the mortality rate within 2 years is 100%. Besides surgical resection, radiotherapy, local hyperthermia and chemotherapy can also be used. Radiotherapy has been successfully used to control melanoma, which may be the most effective treatment after surgical resection. Judging from the above data, the disease is still serious and difficult to eradicate. I suggest going to the hospital! You can also collect more detailed professional books online for a better understanding. I believe that as long as we understand its pathogenic principle, cooperate with doctors and pay attention to ourselves, we will certainly get better. I wish you good health! Hmm. How interesting