General contact will not happen, but scratching the skin, especially skin scratches, may lead to infection. It is highly irritating and may damage the skin. General stimulation, short time, not a big problem. I look at my hands. Local cryotherapy. The most common method. Local injection of medication can also be used.

Others are relatively rarely used. Topical medications are very slow because the skin is thick and the penetration depth of the medication is limited. Oral drugs are also less effective because the drug is in the epidermis and the drug concentration cannot be maintained stably. At the same time, systemic drugs only treat it, so oral drugs are of little significance.