This cannot be manufactured, it can only be extracted. For plants, for example, growth hormone is auxin, which can be secreted at the bud tips of plants; for animals, look at the following.
/view/264193.htm
Growth hormone The chemical component of growth hormone in higher animals and humans is protein. The chemical component of auxin in plants is indole acetic acid, which is a hormone secreted by the anterior lobe of the pituitary gland that can promote body growth. Growth hormone can indirectly promote the formation of epiphyseal cartilage during the growth period by promoting the production of auxin mediators in the liver, promoting the growth of bone and cartilage, thereby increasing the height of the body. Growth hormone also has an impact on intermediate metabolism and energy metabolism. It can promote protein synthesis and enhance the uptake and utilization of important elements such as sodium, potassium, calcium, phosphorus, and sulfur. At the same time, by inhibiting the consumption of sugar, it accelerates fat decomposition and makes energy sources from Sugar metabolism shifts to fat metabolism. When a person is young, if the secretion of growth hormone is insufficient, growth and development will be retarded and the body will become extremely short, which is called "dwarfism"; if the secretion of growth hormone is excessive, it can cause excessive growth of various parts of the body, especially bone growth, leading to Abnormally tall stature is called "giantism". In adulthood, the epiphyses have fused and long bones no longer grow. At this time, if growth hormone is secreted too much, it will stimulate the proliferation of extremity bones, facial bones, soft tissues, etc., manifesting as hands, feet, nose, mandible, ears, tongue, liver, The kidneys and other internal organs show disproportionate enlargement, which is called "acromegaly". If gigantism and acromegaly are caused by tumors of the anterior pituitary gland, local radiation therapy or surgical resection can be performed. High-dose estrogen can inhibit the secretion of growth hormone by the pituitary gland. Hormone treatment should be given as early as possible for dwarfism. Human growth hormone has a significant effect on dwarfism. Due to the difficulty in the source of growth hormone, the clinical application of growth hormone has not been widely carried out so far. At present, scientists have tried genetic engineering methods to isolate the human growth hormone gene from the chromosomal DNA chain, recombined it into a plasmid, and transformed it with E. coli in order to produce human growth hormone through fermentation. Therefore, clinical application is expected to be promoted. In addition, some children with dwarfism do not have fewer growth hormone-secreting cells in their pituitary gland. The pathogenesis of the disease may involve degenerative changes in the neurosecretory cells of the hypothalamus, leading to a lack of growth hormone-releasing hormone. At present, synthetic human pancreatic growth hormone-releasing factor is being used to treat this kind of children, and certain results have been achieved.
Growth hormone can promote human growth and regulate substance metabolism in the body. Growth hormone mainly increases blood sugar by inhibiting the utilization of glucose by muscles and adipose tissue, while promoting gluconeogenesis in the liver and decomposing glycogen. Growth hormone can promote lipolysis and increase plasma free fatty acids. When hungry, insulin secretion decreases and growth hormone secretion increases, so the utilization of glucose in the blood decreases and the utilization of fat increases. At this time, the levels of glucose and free fatty acids in the plasma increase.
Using medication to increase height is not the best way
Ma Hongwei, director of developmental pediatrics at the Second Affiliated Hospital of China Medical University, believes: At present, short stature in children caused by diseases is rare, so it is recommended Children with short stature should not blindly rely on drugs to "increase height", but should go to the hospital's specialized outpatient clinic to understand the cause and provide symptomatic treatment.
Dr. Ma introduced: Currently, more than 300 diseases have been found to be associated with short stature, including: malnutrition, congenital ovarian agenesis in girls, pituitary dwarfism, abnormal bone development, etc. For children with low secretion of growth hormone caused by diseases, different drugs can be used to increase growth hormone. Only by going to the hospital for early examination to find out the cause can symptomatic treatment be achieved.
Regarding the current situation where many parents buy expensive "height-increasing drugs" for their children, Wang Shujie, director of developmental pediatrics at Shenyang Maternal and Child Health Center, said: The various height-increasing drugs currently promoted on the market are not suitable for children. Every child, for example: many children are short due to low thyroid function. Once a child's thyroxine level is found to be low, just taking thyroxine tablets can stimulate the secretion of growth hormone; and many short girls should not take it easily. For all kinds of height-increasing drugs, you should first consider whether there is congenital ovarian hypoplasia. After going to a regular hospital for B-ultrasound examination and chromosomal examination, growth hormone treatment can be used after confirming the diagnosis.
Finally, child development experts remind parents: To increase children’s height, they need to start with scientific nutrition, appropriate exercise, and adequate sleep. Parents must not blindly trust height-increasing drugs and height-increasing instruments, so as not to miss the best opportunity for their children’s growth and development. opportunity.