In our country, the prevalence rate of oral diseases is as high as 97.6%. Almost everyone has experienced oral discomfort, among which pulp diseases are the most difficult to treat. The World Health Organization has classified pulpitis and pulp diseases as the most difficult to treat. Necrosis, tumors and cardiovascular diseases are listed as the three key diseases for human prevention and treatment.
The importance of dental pulp to teeth is like the relationship between tree roots and trunk. If there is a problem with the roots, the trunk will not be able to continue to grow. In the same way, inflammation or even necrosis of the dental pulp will directly affect the teeth. of growth.
Recently, the Stomatological Hospital of the Air Force Medical University announced its major medical research results to the outside world: After nearly 20 years of unremitting efforts, Professor Jin Yan of the hospital’s Tissue Engineering Center successfully achieved dental pulp regeneration and reduced the risk of human oral diseases. Treatment reaches a new milestone.
After searching and comparing, there are currently no literature reports with the same content on this topic at home and abroad. It can be said that this is a worldwide scientific research achievement!
Professor Jin Yan’s team has applied this technology to nearly 50 patients aged 7-12 years old, and all have been successful, including the 8-year-old girl Niuniu (pseudonym).
Tooth regeneration in young patients
Niu Niu accidentally knocked her front teeth out of play and did not do any oral treatment at that time. Suddenly one day, Niu Niu had a high fever and came to the hospital. The doctor told her Niuniu’s parents suffered from pulp inflammation of the necrotic front teeth.
Later, Niuniu’s dental pulp was diagnosed as pulp necrosis by the Stomatological Hospital of Air Force Medical University. In the past, "root canal treatment" was usually used for this kind of cases. This treatment method has been used for more than 200 years. Specifically, it is manually performed by a dentist to completely remove the pulp cells in the tooth pulp cavity and root canal multiple times. Fill with biological material.
However, due to the lack of nutritional supply, although the teeth are preserved after filling, they will gradually become brittle, discolored, and unable to sense cold and warm, especially when biting hard objects, they are easily broken.
Considering that Niuniu is young and losing her natural teeth will have an impact on her future life, the hospital decided to use the latest dental pulp regeneration technology for Niuniu.
The doctor obtained dental pulp stem cells from the two deciduous teeth that were about to fall off in Niuniu’s mouth. After culturing these stem cells in vitro for about a month, they formed dental pulp aggregates the size of rice grains and then implanted them into Niuniu. In the necrotic pulp cavity, the implanted pulp polymer can survive.
Now Niuniu’s teeth are growing well, which once again proves the success of this technology.
At present, the Stomatological Hospital of the Air Force Medical University has published this paper in the authoritative American journal "Science Translational Medicine" which is highly influential in the international academic community, attracting widespread attention from international colleagues.
The successful development of this technology has changed the traditional dental treatment concept of mankind for more than 200 years, especially for the next step of research in the field of tooth regeneration, which is an important milestone. After clinical promotion and application, it will surely bring good news to the majority of dental patients again.