Colla Corii Asini not only has the function of nourishing blood and caring skin, but also has important nourishing functions such as replenishing essence and strengthening brain, delaying aging, supplementing calcium, inhibiting tumor, regulating immunity and preventing sub-health. Ejiao is a tonic for men, which has long been recorded in historical documents. During the Three Kingdoms period, the famous doctor Bielu emphasized that Ejiao could treat male fatigue and emaciation, and it was recorded in Compendium of Materia Medica that Ejiao could treat male joint pain. In modern clinical application, Ejiao has a certain therapeutic effect on male impotence, sexual dysfunction and sexual injury.