2. nosebleeds or nosebleeds.
3. Symptoms of pain and numbness. When the tumor is located at the bottom of maxillary sinus, it often causes toothache symptoms by compressing the superior alveolar nerve or invading the alveolar downward. The tumor developed to the face or the bottom of the orbit. Due to the involvement of infraorbital nerve, swelling and pain in one side of infraorbital and cheek, or numbness in one side of cheek, upper lip and upper teeth may occur. When the tumor penetrates the posterior outer wall of maxillary sinus and invades pterygopalatine fossa, severe sphenopalatine neuralgia can occur, which is manifested as tingling in the nasal root, orbit, cheek and maxillary alveolar of the affected side, and can radiate to the ear and temporal area. In the late stage, the pain is unbearable because the tumor invades the orbit or skull base.
4. Tears and diplopia, decreased vision. Involve nasolacrimal duct, orbit, eye muscle, optic nerve or eye motor nerve, leading to tears, eyeball displacement, dyskinesia, diplopia, decreased vision and even blindness.
5. When the sphenoid sinus tumor involves the optic foramen and the nerves and vessels of the supraorbital fissure, it will cause deep orbital pain, skin numbness around the orbit, ptosis, eye fissure shrinkage, eyeball fixation, diplopia and blindness, which is called orbital apex syndrome.
6. Ear symptoms. Tumor invading eustachian tube leads to deafness, hearing loss and other symptoms of secretory otitis media.
7. It's hard to talk. When the tumor invades pterygopalatine fossa, infratemporal fossa and temporal fossa, it can involve pterygoid medial and lateral muscles, masseter muscles and temporal muscles, and the mandibular joint is limited, making it difficult to open the mouth.
8. Cachexia, manifested as fatigue, anemia and physical decline. At this time, cervical lymph nodes and distant metastasis, intracranial complications and arterial invasive bleeding often occur.