Global Asthma Prevention and Treatment Initiative, "The Impact of Allergic Rhinitis on Asthma" and "Guidelines for the Diagnosis and Treatment of Allergic Rhinitis" (ARIA2008 revised version update) put forward very important practical concepts: due to allergic rhinitis, Asthma (or adenoid hypertrophy or allergic rhinitis-asthma syndrome) usually requires long-term treatment, so allergy patients or parents of children should establish an effective and relatively fixed communication channel with their doctors to communicate in a timely manner that may arise during treatment. problem. At present, in view of the incomplete treatment of allergic rhinitis by simple drug treatment, non-drug anti-allergic probiotics are proposed to adjust allergic constitution and balance immune function therapy. It is recommended to supplement Kangminyuan granules composed of anti-allergic probiotics, and use anti-allergic probiotics Kangminyuan. Adjust your allergic constitution to lay the foundation for solving the following common allergic problems!

The website editor searched some professional websites for information on the most common problems encountered by patients with allergic rhinitis. After sorting out, he summarized the following common questions. The system’s answers are as follows:

1. Problems with drug reduction:

Asthma, allergic rhinitis, allergic rhinobronchitis, postnasal drip syndrome, and adenoid hypertrophy usually require 3-4 months to stabilize the condition. Treatment can only be reduced after a month. Reduction is a slow adaptation process. At the same time, it is also necessary to have corresponding auxiliary methods to regulate allergies. While controlling allergic rhinitis, allergic asthma and allergic rhinobronchitis with drugs, supplementation is required. The anti-allergic probiotic Kangminyuan corrects immune disorders and adjusts allergic constitution to help patients easily solve the problem of drug reduction in the treatment of allergic rhinitis and asthma. The anti-allergic probiotic Kangminyuan assists in drug reduction: from drug-free asymptomatic state to low dose Asymptomatic state, and then to asymptomatic state with trace amounts until drug-free and asymptomatic state. If the dose is reduced too fast, the condition will relapse and all efforts will be wasted. Usually, the condition is evaluated every 3 months, and the doctor is consulted or combined with the stable state of allergic rhinitis remission period to decide whether to reduce the dose. For patients and children with asthma, allergic rhinitis, allergic rhinitis asthma syndrome and allergic rhinobronchitis, continuous The duration of drug reduction and maintenance treatment takes 2-3 years, and children with simple adenoid hypertrophy need at least 4-6 months of treatment. Aspirin-induced asthma, chronic obstructive pulmonary disease (emphysema, cor pulmonale), refractory asthma, and steroid-resistant asthma take longer.

2. Problems with disease recurrence or poor initial efficacy:

Strictly follow the doctor’s instructions and slowly reduce the dosage as directed by the doctor, and the disease will not relapse. Relapses are often associated with exposure to allergens (inhalants or foods), respiratory infections (or colds), chemical odors or irritating gases, changes in temperature (into cold) and humidity, and smog. The second reason is that the treatment is not standardized or the treatment is disconnected, such as the patient's poor compliance with the doctor's instructions or some reasons leading to insufficient medication dosage or too rapid reduction. It may also be related to immunotherapy (non-drug anti-allergy probiotics Kangminyuan IgE-lowering immunotherapy) or desensitization treatment that has not kept up. Regarding the easy relapse of the disease, another very important link is: as the condition improves, the treatment method of the patient or child becomes irregular, the drug is not inhaled properly and the inhaled dose is insufficient. auxiliary programs such as anti-allergic probiotics Stopping Kangminyuan supplementation when symptoms are good is the most common and important reason for the recurrence of asthma, rhinitis or adenoid hypertrophy. If you think about it carefully, how can you effectively and comprehensively control allergic inflammation in the upper and lower respiratory tract with only a small amount of atomized drugs (microgram-level drugs) and insufficient inhalation? When inhaling through the nose, you should inhale during nasal ventilation, and use a physiological seawater nasal irrigator to clean the nasal cavity 15 minutes before inhalation. Especially if you have thick or sticky mucus, you must use a physiological seawater nasal irrigator to rinse the nasal cavity. Rinse out the nasal mucus, otherwise the inhaled medicine will easily stick to the nasal mucus, which will obviously affect the drug's contact with the mucous membrane and lead to poor efficacy.

3. Side effects of inhaled hormones:

Because inhaling microgram-level trace hormones is the fastest and most effective method to treat allergic rhinitis and control allergic asthma, and it is Local treatment is mainly used and there is less systemic absorption, so inhaled hormones have few side effects. Inhaled budesonide has not been found to inhibit adrenocortical function and the hypothalamic-pituitary-adrenocortical axis when the recommended therapeutic dose is used correctly, and no side effects such as Cushing's syndrome, such as edema, obesity, osteoporosis, and hirsutism, have been found. According to a clinical observation of a large British sample of inhaled budesonide for 2 years, the results confirmed that it will not affect the growth, development and height of children. ① Rinse your mouth in time after inhalation (you should inhale and rinse once) and spit out the mouthwash are key measures to avoid the systemic side effects of oral inhalation of steroids in treating asthma and allergic rhinitis asthma syndrome. A few patients may experience hoarseness and should use throat gargling. A very small number of children may occasionally develop oral thrush, which is also related to not gargling in time after inhalation. ② For patients who treat allergic rhinitis and adenoid hypertrophy through nasal inhalation, there may also be drug deposition in the throat due to slow and deep inhalation. , so it is best to rinse your mouth in time after inhaling through the nose, and it is also best to use a cotton swab dipped in saline to clean the nasal vestibule (that is, the nostrils) ③ For infants under 3 and a half years old who use a mask-type infant atomizer, You should wash your face and rinse your mouth immediately after inhalation.

4. Regarding the side effects of anti-allergic drugs:

Since the first-generation anti-allergic drugs such as chlorpheniramine and phenergan have strong central nervous system inhibitory effects, they cannot be used with them for a long time. Large doses are used for the treatment of asthma, allergic rhinitis, allergic rhinitis asthma syndrome, etc., while second-generation anti-allergic drugs (such as aspirin, loratadine, terfenadine, cetirizine and ketone Fen, etc.) have obvious cardiotoxicity and can easily lead to sudden cardiac death, and have been gradually discontinued abroad. At present, we use third-generation antihistamine drugs such as levocetirizine, desloratadine, and fexofenadine, which are safe and have few side effects. They are suitable for long-term use and have very small side effects. They are currently The most commonly used drugs in advanced foreign countries. Note (Levocetirizine is not cetirizine, and desloratadine is not loratadine. Although the word is different, the side effects are many times different. Pay attention to identification)

5. Treatment Cold problems occur during the treatment process:

During the treatment process, if there is yellow phlegm or yellow thick nasal discharge or fever, it is usually combined with respiratory infection or cold. Children with allergic constitution should try not to use antibiotics. (Because most colds are viral infections, antibiotics are not the first choice. Secondly, antibiotics have greater side effects for children with allergic constitutions.) If you have yellow or sticky mucus or you feel like you have mucus but cannot blow it out, you can use a physiological seawater nasal irrigator. Rinse the nasal cavity and instill the nose with Levofloxacin eye drops (2 drops on each side, 3 times a day). When instilling the nose, lie flat at the end of the bed, with your head stretched out from the end of the bed in a backward position, with the nostrils pointing upward, and instill the nose gently, and keep it for 2- 5 minutes to prevent the medicine from flowing into the mouth and causing a bitter taste. If the fever is below 38.5 degrees, you can take an alcohol bath, and if the temperature is above 38.5 degrees, you can take antipyretics. Most colds can be relieved within a few days if there is no sign of relief after treatment. Go to the local hospital to check the blood routine. If the white blood cells (WBC) are increased, that is, the blood count is usually high, it may be a bacterial infection. Antibiotics (such as cephalosporins) should be considered. If the blood count is not high but the lymphocytes are high, it may be a respiratory virus infection. Viruses For infections, just drink more water and rest. Secondly, if the infection does not heal after repeated treatments, you should also consider mycoplasma infection. If mycoplasma antibodies are positive, you can consider treating it with erythromycin enteric-coated tablets (azithromycin has cardiac side effects, so use it with caution). Budesonide or anti-allergic drugs should not be stopped at will during infection or cold, but immunomodulators (such as Yupingfeng, Spleen Peptide, Chest Peptide, Shenqi Granules, etc.) can be suspended during the recovery period of fever and cough. Or the symptoms of the nose will worsen. For clear nasal discharge or dry cough, you can add one puff of budesonide. Usually, it can be recovered within a week without using too many medicines. The treatment of yellow or sticky nasal discharge is the same as above.

6. Some parents asked about the problem that the adenoids have atrophied but the tonsils are still large. Because the tonsils are chronically enlarged due to mouth breathing, oral inhalation of bacteria, viruses or allergens, it is necessary to treat the adenoids after atrophy. This kind of chronic tonsil hypertrophy is different from the hypertrophy of acute tonsillitis, which slowly recovers after breathing through the mouth for a period of time. Usually, the effect of drugs is not good, but it only takes time to recover.

7. Tonsillitis. Questions about the time and efficacy of allergy treatment and immunotherapy:

Usually desensitization treatment takes 2-3 years, so continuous treatment is required. Desensitization treatment and immunotherapy cannot cure allergic constitution, but are a kind of allergic constitution. The treatment of allergic diseases by improving allergic constitution is difficult to cure, but it has a fundamental effect and can effectively improve the condition. Desensitization treatment includes sublingual drops and injections, and immunotherapy is mostly taken orally. Treatment. Usually, patients over 4 years old who are mainly allergic to dust mites are suitable for desensitization treatment. Immunotherapy (including traditional Chinese medicine immunotherapy and biological agents) is suitable for children over 2 years old and adults, and it also requires at least 3 months or 6 months. month of treatment. Immunotherapy in adults takes longer. Immunotherapy drugs usually have no or few side effects. Desensitization treatments also have very few side effects.

8. Treatment issues:

Allergic disease is caused by allergic constitution and is a chronic disease, so it requires long-term treatment. Each person's course of treatment varies according to the condition (severity and presence of complications). For example, some asthma is combined with allergic rhinitis, some adenoid hypertrophy is combined with allergic rhinitis or bronchitis, and some even have allergic rhinitis and allergies. Conjunctivitis, allergic asthma, adenoid hypertrophy and eczema are all suffered at the same time, so the specific courses of treatment and the length of each course of treatment are also different. The current internationally popular treatment plans are individualized treatment plans. The length and number of each course of treatment vary from person to person and the condition. Moreover, this plan is usually a long continuous process, so it requires doctors, patients and children to Close cooperation with parents.

9. The special significance of immune regulation in allergy treatment:

The combination of anti-allergic probiotic strains Lactobacillus salivarius and Lactobacillus gasseri creates Kangminyuan probiotics to create a non-drug anti-allergy Microecological immune new therapy.

Allergy is a stealth killer that destroys the immune system. Repeated allergies will highly activate the body's immune cells and induce various inflammatory reactions, such as allergic rhinitis, allergic asthma, children's eczema, urticaria and drugs, Atopic dermatitis caused by cosmetics, food, and pollen allergies are all manifestations of allergies. Research shows that the number of Lactobacillus salivarius in people with allergic constitution is much lower than that in healthy people, which is a prerequisite for allergic reactions.

The lack of Lactobacillus salivarius in the human body will increase the IgE antibodies in the serum and insufficient secretion of IFN-γ in spleen cells, inducing various allergic reactions in the skin and mucous membranes. Su Weizhi, a medical doctor from Taiwan Dongyu Biotechnology, found that the number of Lactobacillus salivarius in the human intestine is sufficient, and allergic reactions will not occur even if continued exposure to allergens; supplementing Lactobacillus salivarius is directly related to the occurrence and severity of allergic reactions.

Four major medical centers in Taiwan have confirmed through quantitative supplementation of Lactobacillus salivarius in allergic children: 1. It helps to reduce the production of specific IgE antibodies in the serum; 2. It helps to promote the secretion of IFN-γ in spleen cells. quantity. After 3 months of supplementation, the number of salivary bacteria in the allergic children's bodies basically reached the normal value. When the supplement was stopped, follow-up showed that no allergic reactions occurred in the allergic children within 3 years. Lactobacillus salivarius is a native strain extracted from the digestive tract of healthy children. It is safe and efficient and can be supplemented by infants and pregnant women. The health food developed by Dongyu Biotechnology in Taiwan: Kangminyuan Probiotics, a compound bacteria granule with Lactobacillus salivarius and Lactobacillus gasseri as the main ingredients, greatly reduces the individual differences in allergies. This anti-allergic probiotic has been launched in mainland China. Products cannot replace medicine.

10. Exercise issues:

Exercise is an important measure to increase physical fitness and body resistance. It can complement each other in improving allergic constitution when combined with immune or desensitization treatment. Exercises suitable for asthma, allergic rhinitis patients or children include swimming, morning jogging, Tai Chi, yoga, qigong, relaxed badminton, respiratory gymnastics and radio gymnastics. Swimming is a relatively gentle sport, which can not only exercise physical fitness, but also adjust breathing exercises and cold-resistant exercises. However, allergic constitutions are often allergic to disinfected water, and swimming pools are usually disinfected in the morning, so it is best to swim in the afternoon or evening. Yoga, Qi Gong, and Tai Chi can also be used to modify breathing exercises and endurance exercises. For other sports such as morning jogging and badminton, it is appropriate for the heart rate to not exceed 100 beats/minute.

11. Dietary issues:

There is no need to strictly limit foods with mild allergies. The principles of eating less, freshly and heated should be followed. Eating less frequently (the key is to control the amount of food) can develop tolerance (antibodies) and gradually eliminate allergies. For example, if you are allergic to milk, you can eat 1 ml a day first, 2 ml a day in the second week, and every day in the third week. Take 4 ml... If you are allergic to a certain dose, just lower the dose by one dose and take one more dose before adding it again. The same goes for other foods. Don’t eat seafood from the refrigerator, eat it fresh and don’t eat it raw. Certain foods that can induce severe allergies and are not commonly eaten should be avoided, such as mangoes, silkworm chrysalis, buckwheat, peaches, etc. Allergy patients should not eat spicy food. Cough and asthma patients should not eat foods that are too sweet, too salty and too cold. Regarding the problem of children eating ice cream and sorbet, they can eat it, but they should eat less at the beginning. For example, eat 1/8 ice cream or sorbet every day in the first week, and 1/4 in the second week. Gradually let the child adapt, and you can also increase the amount. Cold tolerance.

12. Conclusion

Parents’ patience and long-term careful observation are often required for changes in children’s condition, and the judgment of the severity of the condition and the change of drugs and the increase or decrease of dosage in the treatment plan often require It needs to be judged and decided by doctors and implemented by parents. This requires parents and doctors to have a more effective and fixed communication channel. At present, most hospitals only see a patient for a few minutes, and the doctor's treatment mode is often changed in outpatient clinics. Continuous observation, long-term treatment and accurate dose reduction of chronic diseases such as asthma, allergic rhinitis and adenoid hypertrophy are all important. Very disadvantageous.

Children who are prone to genetic allergies should start to pay attention to the adjustment of their allergic constitution after allergic symptoms occur. Non-drug immune regulation can be used to supplement the anti-allergic probiotic Kangminyuan on weekdays, which can adjust their allergic constitution, help reduce allergic symptoms, and at the same time prevent allergies and reduce the risk of allergies. The occurrence of allergic diseases.