Condyloma Acuminatum is a sexually transmitted disease caused by human papillomavirus (HPV) infection. At first, it was reddish papules, which gradually increased and aggravated. If the disease continues to develop without treatment, it can fuse into papillary, cauliflower-like or cockscomb-shaped, with pedicle at the root and white, dirty gray or red surface, which may have itching, burning pain and stench. Women often occur in vaginal orifice, labia majora, clitoris, urethral orifice, perianal region and perineum, and a few patients' vaginas and cervix can also occur, while men often occur in prepuce frenulum, coronary sulcus, prepuce, urethra, penis, perianal region and scrotum.