Yes, it is one of the most commonly used penicillin broad-spectrum β -lactam antibiotics, and its half-life is about 6 1.3 minutes. It is one of the widely used oral penicillins at present, and it is forbidden for those who are allergic to penicillin and those who are positive in penicillin skin test. Its function is anti-bacterial and anti-inflammatory, and its specific application scope is as follows: Amoxicillin is suitable for infections caused by the following sensitive bacteria (strains that do not produce β -lactamase): 1. Upper respiratory tract infections caused by hemolytic streptococcus, streptococcus pneumoniae, staphylococcus or Haemophilus influenzae, such as otitis media, sinusitis, pharyngitis and tonsillitis. 2. Urogenital tract infection caused by Escherichia coli, Proteus mirabilis or Enterococcus faecalis. 3. Skin and soft tissue infections caused by hemolytic streptococcus, staphylococcus or Escherichia coli. 4. Lower respiratory tract infections, such as acute bronchitis and pneumonia caused by hemolytic streptococcus, streptococcus pneumoniae, staphylococcus or Haemophilus influenzae. 5. Acute simple gonorrhea. 6. This product can also be used to treat typhoid fever, typhoid fever carriers and leptospirosis; Amoxicillin can also be used in combination with clarithromycin and lansoprazole to eradicate Helicobacter pylori in stomach and duodenum and reduce the recurrence rate of digestive tract ulcer. Adverse reaction: 1. Gastrointestinal reactions such as nausea, vomiting, diarrhea and pseudomembranous enteritis. 2. Allergic reactions such as rash, drug fever and asthma. 3. Anemia, thrombocytopenia and eosinophilia. 4. Serum transaminase can be slightly increased. 5. Double infection caused by candida or drug-resistant bacteria. 6. Occasionally, symptoms of the central nervous system such as excitement, anxiety, insomnia, dizziness and abnormal behavior can be seen. Note: 1. Penicillins occasionally cause anaphylactic shock, especially in patients with allergic history to penicillin or cephalosporins. Be sure to ask about the history of drug allergy in detail and do a penicillin skin test before taking the medicine. If anaphylactic shock occurs, first aid should be given on the spot, and the airway should be kept clear, oxygen should be inhaled, and adrenaline and glucocorticoid should be used. 2. Patients with infectious mononucleosis are prone to rash when using this product, and should avoid using it. 3. Patients with a long course of treatment should check their liver, renal function and blood routine. 4. Amoxicillin can lead to false positive of urine glucose test with Benedit or Fehling reagent. 5. Use with caution in the following situations: (1) people with allergic diseases such as asthma and hay fever. (2) The elderly and severely impaired renal function may need to adjust the dosage. Medication for pregnant women and lactating women: Animal reproduction tests show that 10 times the dosage of amoxicillin for human does not harm the fertility and fetus of rats and mice. However, there are not enough human controlled studies. In view of the fact that animal reproduction tests can not completely predict human reactions, pregnant women should only use this product when it is really necessary. Because a small amount of amoxicillin can be secreted in milk, breastfeeding mothers may cause baby allergies after taking it. Drugs for children: 1. Probenecid competitively reduces the renal tubular secretion of this product, and the simultaneous application of probenecid and probenecid can increase the blood concentration of amoxicillin and prolong the half-life. 2. Chloramphenicol, macrolides, sulfonamides and tetracyclines interfere with the antibacterial effect of amoxicillin in vitro, but their clinical significance is unknown. Drug interaction: A prospective study involving 5 1 child showed that when the dose was less than 250mg/Kg, amoxicillin would not cause obvious clinical symptoms. It is reported that a small number of patients have renal insufficiency and oliguria due to amoxicillin overdose, but the renal function damage can be reversed after drug withdrawal.