With the increase of age, the skin will gradually appear aging phenomena such as relaxation, weakened elasticity and local depression. The methods we can use to adjust facial contour and shape include filling hyaluronic acid, collagen and autologous fat. Hyaluronic acid and collagen are both good, but the disadvantages are equally obvious. It will be absorbed by the body within nine to twelve months. In addition, because it is liquid, its shape is not fixed and its price is high, so it is not suitable for large-scale filling. Autologous fat comes from itself, has no rejection, is easy to obtain, is quick to operate, has little local reaction, feels good after filling, is easy to be accepted by patients, and can obtain better shaping effect.
Autologous fat is a commonly used filling material for plastic surgery soft tissue filling and shaping at present. Since Neuber put forward autologous fat, it has been the focus of research. In recent 100 years, the range of autologous fat filling has been expanding, which can be applied to facial aging diseases, limb asymmetry, concave scars and defects caused by various reasons. However, it should be pointed out that autologous fat filling faces a problem of fat cell survival. Because if the cells can't survive, the filled fat will be absorbed, resulting in a decrease in the amount of autologous fat and adverse reactions such as infection, liquefaction, necrosis and calcification.
In other words, whether fat cells can survive in autologous fat filling is a problem we have to solve. What methods can improve the survival rate of fat cells?
First of all, in the filling method, ischemic preconditioning can be carried out organically: after ischemic preconditioning (such as delayed operation of fat flap) on the cellulite to be filled, it is found that ischemic stimulation can increase the level of VEGF in adipose tissue and promote the growth of blood vessels in adipose tissue. After transplantation of this kind of adipocytes, the growth ability of blood vessels is enhanced, and the tolerance of adipocytes to ischemia becomes stronger. Therefore, ischemic preconditioning can improve the living surname of fat.
Secondly, the choice of recipient area and donor area. Donor site: Due to the difference of living surnames of lipoprotein lipase (LPL) in different parts of human body, the researchers found that the activity of LPL in thigh adipose tissue was higher than that in other parts, followed by buttocks, lower abdomen and upper abdomen. According to this study and the deep fat distribution in these parts, the lower torso should be the first choice for fat transplantation. Accepting area: Karacaogul found that sufficient nutrition and loose space on the muscle surface provided conditions for the growth of fat, so the fat particles filled on the muscle surface were easy to survive.
Finally, Wilmetton nutritional supplements. After autologous fat, Wellmuneβ, Astareal, Uitika, ocean sweet F40, elastin collagen tripeptide and other nutrients should be supplemented. Help cells grow and improve the possibility of survival with fat. These repair components protect our cells like shields, so they are called micro-shields in medicine. Astarot in Vermont can penetrate the cell wall and knock on the door of cells, just like a car carrying other nutrients into cells, while preventing phospholipid molecules from being destroyed by oxidation; Wellmuneβ promotes hematopoietic function, including the production of granulocytes, monocytes and red blood cells; Ocean sweet F40 can generate moisturizing factor to protect hyaluronic acid and prevent collagen fiber accumulation in concave and convex parts. Elastin collagen tripeptide can promote the normal growth of collagen and promote the healing of cell injury. It is also feasible to repair cells by supplementing nutrition.
It is human nature to pursue beauty, and I hope everyone can become a beautiful self.
This article draws on:
Research progress on improving the survival rate of autologous fat transplantation: research progress of facial autologous fat transplantation, Jin Shanxu, Qi Fazhi