For people with many wrinkles, wrinkle needles are the bane. I used to have a wrinkle needle in Mianyang St. Bolier Medical Beauty and Plastic Surgery Department, but the wrinkle needle has certain timeliness and needs to be replenished regularly. The effect of wrinkle removal with one needle can generally last for 6- 12 months. If you want to maintain it for a long time, the specific time varies from person to person. It can be maintained for a long time after three anti-wrinkle injections, and there is no obvious rebound within 2-3 years.