The First Hospital of Shijiazhuang has four centers approved by the Health Department: Shijiazhuang Acute Myocardial Infarction Treatment Center, Shijiazhuang Medical Plastic Surgery Center, Shijiazhuang Health Examination Center and Shijiazhuang Medical Rehabilitation Center. Burn plastic surgery is a key development discipline in Hebei province, and cardiovascular medicine, oncology, anesthesiology, respiratory medicine, neurology, general surgery, gastroenterology, ophthalmology and neurosurgery are municipal key disciplines. Pediatrics, endocrinology, nephrology, oral and maxillofacial surgery and ultrasonic diagnosis are the key disciplines in Shijiazhuang. The hospital now has three campuses: headquarters, central hospital campus and western hospital campus.

The technology of minimally invasive and non-invasive comprehensive treatment of tumor in the headquarters of the First Hospital of Shijiazhuang is leading in the province. Cardiovascular and cerebrovascular intervention, arrhythmia, hypertension, lung cancer and breast cancer have formed characteristics.

The central hospital focuses on the construction of Hebei myasthenia gravis hospital, which is the diagnosis and treatment center of myasthenia gravis in Hebei Province.

Xiyuan District was the ninth hospital of the former city (the municipal traffic hospital), and now it is the first eye hospital of Shijiazhuang City and the first public eye hospital in the provincial capital.