Animal skin nevus is a congenital melanocyte nevus. Because of its large area and diameter of more than 20 cm, it is called a giant melanocyte nevus with the most coarse black hairs on its surface, so it is called an animal skin-like nevus. In some patients, most of the trunk or the whole limb may be covered with moles, and the larger the area, the more likely it is to become malignant than pigmented nevus, and some of them are as high as 10%. The disease can be treated in hospital dermatology or plastic surgery, and surgical resection is the best choice. Some patients need multiple surgical excision or catgut embedding expander surgery, and laser treatment can also be selected.