Mother-of-pearl is an organic substance made of shellfish, which usually does not produce magnetism. If you mean that mother-of-pearl has a magnetic substance, you can try the following methods to degauss it:

1. Use a magnetic field degausser: You can buy a portable magnetic field degausser in jewelry stores or some special stores. Put the mother-of-pearl jewelry into the demagnetizer and use it according to the instructions. This method is simple and convenient, and can quickly remove the magnetic substances attached to mother-of-pearl.

2. Use a magnet: put a strong magnet near the mother of pearl, and then move it slowly until it leaves the mother of pearl. This process may take several minutes or even longer to ensure that the magnetic substance is attracted to the magnet. Please be careful when using magnets to avoid direct contact with mother-of-pearl, so as to avoid scratching or damage.

No matter which method is adopted, care should be taken to ensure that it will not cause any damage to mother-of-pearl. If you have no confidence in the operation, it is recommended to go to a professional jewelry store for help.