1, different components. 5400 glue is a universal transparent super glue. The main component of glue is epoxy resin. Ergo5800 is an instant adhesive made of modified cyanoacrylate.
2, the action temperature is different. 5400 glue can only work at room temperature, and it will fail if the temperature is too high or too low. Ergo5800 can be used at any temperature and remains sticky at both high and low temperatures.