The impact on human body is mainly to restore fatigue; Prevention of anemia; Help metabolism and so on. Many places are used as medical AIDS. But it has not been clinically proved to be effective. At most, they will say: the body will be lighter and the pain will be relieved. If you take it, there have been deaths. What clinical researchers think is dangerous. It will have a bad effect on the kidneys. But in Japan, it is sold in necklaces and bracelets as a health care appliance in the jewelry industry. Very expensive %D%A Up to now, it has not been found that germanium is an essential trace element for human body, nor has it been found that organisms are diseased due to germanium deficiency, so it is not necessary to supplement germanium under normal circumstances, because human body can ingest enough germanium in normal diet. At present, it is found that the beneficial biological effects of germanium are closely related to the existing forms, and it seems that there is no obvious physiological activity. Only some organic germanium compounds can show certain physiological activities. %D%A 1。 Distribution and metabolism of germanium in the body %D%A All kinds of natural foods contain germanium to varying degrees. The daily intake of germanium for adults is about 400-3500ug, so germanium is everywhere in the body. Some enzyme proteins in the body, cerebral cortex and gray matter all contain trace elements of germanium. %D%A Second, organic germanium compounds with physiological activities %D%A The most studied organic germanium compounds include organic germanium sesquioxides, derivatives and sulfur-containing coordination organic germanium compounds, and their physiological activities are the most obvious. %D%A germanium has obvious anti-tumor and anti-inflammatory activities, and there are many other types of organic germanium compounds, most of which have biological effects such as anti-tumor, anti-inflammatory, immune resuscitation and sterilization, but they can only be used as medicine because of their great toxicity. %D%A Third, the relationship between organogermanium compounds and tumors %D%A Organogermanium 132 and spirogermanium have obvious anti-tumor activity and low toxicity, especially no bone marrow toxicity. They have great potential in preventing and treating tumors and assisting radiotherapy and chemotherapy, and have entered the clinical trial stage. The possible mechanisms of %D%A organogermanium compounds inhibiting tumor activity include enhancing immunity, scavenging free radicals and resisting mutation. In many bioactive organic germanium compounds, strongly electronegative atoms such as oxygen, sulfur and nitrogen are usually coordinated with germanium atoms. Because they absorb electrons, the electron clouds around germanium atoms deviate from the nucleus and form a positive center. When organic germanium compounds meet tumor cells, its normal center can increase the potential energy of tumor cells and reduce their activity, thus playing a role in inhibiting and killing tumor cells, that is to say, organic germanium compounds inhibit tumor activity. %D%A In addition to anti-tumor and immune resuscitation, germanium also has beneficial biological effects, including stimulating the function of hematopoietic system, inhibiting cell growth, promoting antibacterial disappearance, and promoting plant growth. The effect on the blood system is mainly manifested in stimulating the increase of the number of red blood cells and hemoglobin in the blood, which has a certain effect on the treatment of anemia.