Face-lifting needles still have some side effects. The key is to find qualified regular hospitals and doctors with high professional knowledge to operate. The dosage of face-lifting needle should be controlled well. In general, after injection of botulinum toxin needle, local adverse reactions include myasthenia gravis and a series of reactions caused by the spread of botulinum toxin to adjacent muscle tissues. These clinical manifestations are closely related to the injection site and the dose of botulinum toxin.