Radiation is harmful to the skin during radiotherapy for patients with hilar cholangiocarcinoma. If the skin reaction is mild, such as local pigmentation, dry dermatitis, etc., no special treatment is needed. If the skin reaction is serious, such as redness and ulceration of the skin in the radiotherapy area, symptomatic treatment is needed. When patients have skin ulceration after radiotherapy, the affected skin should be kept clean and dry to avoid infection. Don't blindly apply skin care products. Be sure to use drugs to promote skin healing under the guidance of a doctor. If the skin of the irradiated area is ulcerated and infected, anti-inflammatory drugs should be applied in time. In addition, you can also take some Chinese medicine to improve symptoms. Yuan Xifu suggested that Chinese medicine can not only reduce the damage of radiotherapy to the body, improve the clinical symptoms of patients, enhance immune function, improve the sensitivity of the body to radiotherapy, improve the therapeutic effect of radiotherapy, and help patients successfully complete the whole course of treatment.