Wright syndrome is a syndrome characterized by acute encephalopathy and hepatic steatosis in infancy and childhood. Its onset age is mostly from 6 months to 15 years old, which is rare in adults. The etiology is still unclear, which may be related to virus infection, drugs and toxins, and may also be related to heredity. Its clinical manifestations mainly include some precursor symptoms, such as fever, cough, runny nose, sore throat and persistent vomiting. Symptoms of acute encephalopathy will appear in a few days. With the aggravation of the disease, there may be changes in consciousness, convulsions, indifference, lethargy and coma. In severe cases, brain hernia and respiratory failure caused by brain edema directly lead to death. Liver disease is mild, the liver is slightly swollen but not swollen, and there is generally no splenomegaly and jaundice. Neurological examination showed pathological reflex, inverted horn arch and increased intracranial pressure. Laboratory tests often show leukocytosis, mainly neutrophils. Liver function test showed that serum alanine aminotransferase, aspartate aminotransferase and phosphokinase increased significantly, and most of them returned to normal in a week or so. Cerebrospinal fluid examination showed no obvious abnormality except increased pressure. At present, there is a lack of specific treatment, mainly symptomatic support treatment to correct water and electrolyte disorders, hypoglycemia and acidosis, and symptomatic treatment is to control brain edema; If prothrombin is abnormal and easy to bleed, a coagulant can be given; Keep the respiratory tract unobstructed and intubate or cut the trachea if necessary.