Under the specific guidance of TCM syndrome differentiation theory, TCM treatment of this disease should distinguish between deficiency and excess and evil. From the theoretical point of view of the combination of whole and part, anti-cancer treatment should be combined with strengthening the body resistance and consolidating the constitution, and syndrome differentiation treatment should be combined with disease differentiation treatment. Traditional Chinese medicine believes that the etiology and pathogenesis of lung cancer are deficiency of vital qi, accumulation of phlegm and toxin, and imbalance of zang-fu organs and yin-yang. There are as many as 5~6 specific syndrome differentiation types, but the fundamental reason is "qi deficiency" after careful study. The deficiency of vital qi should be qi deficiency, which does not need to be elaborated; Stagnation of phlegm and turbidity, accumulation of toxin, caused by accumulation of dampness in water and deficiency of qi, is not conducive to transport and transformation; The imbalance of yin and yang of zang-fu organs and the decline of zang-fu functions are also manifestations of qi deficiency. The lung is fine and dirty, the five internal organs are covered with flowers, and the yang is often insufficient, so the "qi deficiency" should be dominated by "yang deficiency". Throughout the doctor's theory, few theories think that "Yang deficiency" is the fundamental pathogenesis of lung cancer. The author refers to the opinions of some scholars (attached), and according to the actual observation and application, confirms the correct pathogenesis, thus guiding clinical treatment and achieving good results. Clinically, it is observed that most lung cancer patients, especially those with early, middle and late lung cancer, are characterized by fat and thin white tongue coating, while other yang deficiency syndromes, such as pale face, listlessness and fatigue, are more or less obvious. After conditioning with Wenyang Fuzheng medicine, it improved, but it basically recovered after stopping using it for a period of time (about 1 month), and it improved again with Wenyang medicine. Therefore, according to the pathogenesis analysis of traditional Chinese medicine and medical practice, the author proves that the fundamental pathological pathogenesis of lung cancer is "yang deficiency", so the method of warming yang and benefiting qi should run through the treatment of lung cancer. Its basic prescription (main prescription of lung cancer) is: ginseng (or American ginseng) 10g, astragalus root 30g, Ophiopogon japonicus 15g, Schisandra fruit 9g, cassia twig 20g, aconite root 30-60g (fried first), dodder seed 15g, Ligustrum lucidum 15g and pilose antler 3g. (1) syndrome differentiation and treatment 1. Syndrome of spleen deficiency and phlegm dampness: cough with excessive phlegm, chest tightness, listlessness, pale complexion, thin stool, pale and fat tongue, white and greasy fur, and slow or slippery pulse. Treatment: invigorating spleen and eliminating dampness, warming yang and benefiting qi, resolving phlegm and resolving hard mass. Prescription: Lung cancer is the main prescription, and drugs for invigorating the spleen and eliminating dampness are selected, such as Atractylodes macrocephala 15g, Poria cocos 15g, Pinellia ternata 10g, Pericarpium Citri Reticulatae 10g, Coicis Semen 15g, Oyster 30g, Fritillaria thunbergii 15g. 2. Syndrome of deficiency of both qi and yin: cough with no phlegm or less phlegm or frothy sputum, or yellow cough with difficulty in coughing, blood in phlegm, chest pain and shortness of breath, vexation and insomnia, constipation due to dry mouth, red tongue, peeling or no fur, and rapid pulse. Treatment: benefiting qi and nourishing yin, warming yang and clearing lung. Prescription: The main prescription for lung cancer is drugs for invigorating qi and nourishing yin, such as Adenophora adenophora 30g, Ophiopogon japonicus 15g, Hedyotis diffusa 30g, Cortex Mori 15g, Radix Rehmanniae 15g, Prunella vulgaris 30g, etc. If there is blood in the sputum, drugs such as Agrimonia pilosa 15g, Charcoal Cirsium japonicum 15g, Colla Corii Asini 10g (dissolved) can be added. 3. Syndrome of qi stagnation and blood stasis: cough, blood in sputum, shortness of breath, fullness or tingling in chest and hypochondrium, dry stool, ecchymosis or purple spots on tongue, thin yellow fur, thin or astringent pulse. Treatment: Warming yang, activating qi, removing blood stasis and resolving hard mass. Prescription: The main prescription of lung cancer is drugs for promoting blood circulation and removing blood stasis, such as Angelica sinensis 15g, Radix Rehmanniae 15g, Semen Persicae 10g, Radix Salviae Miltiorrhizae 15g, Radix Paeoniae Rubra 15g, Fructus Aurantii 10g and Radix Curcumae/kloc. 4. Syndrome of excessive heat toxin: high fever, shortness of breath, cough, thick yellow or bloody sputum, chest pain, bitter taste, thirst, constipation, short and red urine, red tongue, Huang Gan coating and rapid pulse. Treatment: clearing away heat and purging fire, detoxifying and reducing swelling. Prescription: Baihu Chengqi Decoction. Medicinal purposes: gypsum 30g, Anemarrhena asphodeloides 10g, rhubarb 10g, coptis chinensis 10g, houttuynia cordata 30g, dandelion 15g, hairyvein agrimony 15g, Trichosanthes kirilowii 10g, scutellaria baicalensis. This type is a special type of lung cancer, which is mostly a sign of excess heat caused by lung infection and a standard syndrome, but the reality is still "Yang deficiency". According to the principle of "emergency is palliative", the treatment should be clearing away heat and purging fire, detoxifying and reducing swelling, and if necessary, cooperating with intravenous medication. After the condition improves, the main prescription of warming yang and benefiting qi to treat cancer will be modified according to the syndrome. 5. Syndrome of deficiency of both qi and blood: dull complexion, dizziness and fatigue, mental fatigue, spontaneous sweating when moving, shortness of breath and palpitation, loss of appetite, leukopenia, pale tongue, fat tongue, less fur and thready pulse. Treatment: benefiting qi and nourishing blood, warming yang and nourishing yin. Prescription: the main prescription of lung cancer is supplemented with qi-invigorating and blood-nourishing drugs, such as angelica 9g, psoralea corylifolia 15g, fried atractylodes rhizome 12g, antler cream 12g, prepared rehmannia 20g, Amomum villosum 30g, Placenta Hominis 12g, Lycium barbarum 15g, Spatholobus 20g, etc. The symptoms of lung cancer are very complicated and there are many complications. With the development of the disease, syndrome differentiation is also mixed, and Chinese medicine should run through the treatment. Therefore, we must grasp the specific situation and use it flexibly in order to treat it correctly. In order to master medication, you can refer to the following commonly used drugs to choose addition and subtraction. Cough due to excessive phlegm: Fructus Trichosanthis, Radix Platycodi, Semen Armeniacae Amarum, Radix Peucedani, Radix Asteris, Semen Lepidii, etc. Phlegm and blood: Jiejie, Lalang Grass Rhizome, Agrimony, Eclipta prostrata, Bletilla striata, Notoginseng, etc. More difficult to vomit: sea clam powder, Gleditsia sinensis. Spontaneous sweating due to qi deficiency: ginseng, Cordyceps sinensis, Schisandra chinensis, floating wheat, raw astragalus, calcined keel, calcined oyster, etc. Dry mouth and tongue: Trichosanthes, Radix Rehmanniae, Radix Scrophulariae, Rhizoma Anemarrhenae, Radix Adenophorae, etc. Chest pain: Rhizoma corydalis, Radix Notoginseng, Olibanum, Myrrha, Radix Aconiti Lateralis Preparata, and Yunnan Baiyao. Pleural effusion: prickly heat, plantain seed, polyporus, Daphne genkwa, etc. Softening and resolving hard mass: Prunella vulgaris, Fritillaria, Oyster, Squama Manis, Leech, Bombyx Batryticatus, Shā rotto Katakuri, etc. Anti-cancer and tumor suppression: Herba Hedyotidis Diffusae, Solanum nigrum, Rhizoma Paridis, Radix Rubiae, Herba Scutellariae Barbatae, Radix Peucedani, Herba Houttuyniae, Spica Prunellae, Scutellariae Radix, Rhizoma Arisaematis, Rhizoma Pinelliae, Mylabris, Toad, Cordyceps sinensis, Gynostemma pentaphyllum, Radix Arnebiae, Rhizoma Dioscoreae Septemlobae, Rhizoma Dioscoreae bulbiferae, etc. (2) The single prescription is 1. Brucea javanica emulsion injection, 30-80 ml, 500ml of 5% glucose saline, intravenous drip for 20-30 days, with an interval of 10 day, and then the next course of treatment. 2. Pig Qin extract, 40mg per day, intramuscular injection, combined with chemotherapy. Suitable for all types of lung cancer. 3. Fresh Solanum nigrum 30g, daily 1 time, decocted in water, suitable for lung cancer patients with pleural effusion. 4. Lung squamous cell carcinoma: Radix Arnebiae 30g, Concha Ostreae 30g, Radix Sophorae Tonkinensis 15g, Rhizoma Paridis 15g, Prunella vulgaris 15g, Sargassum 15g, Fritillaria 20g, Radix Peucedani 10g. Decoct with water, daily 1 dose. 5. Lung adenocarcinoma Fang Shu Yangquan 30g, Solanum nigrum 30g, Smilax China L. 30g, Oyster 30g, Raw Coicis Semen 30g, Raw Oyster 30g, Rubi 15g, Prunella vulgaris 15g, Shā rotto Katakuri 15g, Fritillaria thunbergii 10g. Decoct with water, daily 1 dose. 6. Xu Changqing 30g, Scutellaria barbata 30g, Hedyotis diffusa 30g, Solanum nigrum 30g, Smilax glabra 30g, Agrimonia pilosa 30g, Dioscorea bulbifera 30g, Rhizoma Paridis15g, Flos Chrysanthemi Indici15g, Radix Peucedani10g, and Radix Platycodi/kloc. Decoct with water, daily 1 dose. 7. Gold powder, snake powder, Rhizoma Arisaematis, Rhizoma Bletillae, coat of Phoenix, dried tangerine peel and Fructus Trichosanthis each 30g, Radix Glehniae 60g, Radix Panacis Quinquefolii15g, Carapax Trionycis preparata 45g, milk powder 20g and cinnabar12g. * * * Grind into fine powder, once 1g, three times a day, and take orally. It is suitable for lung cancer patients with yin deficiency and blood stasis and phlegm and blood stasis. (III) Experience of famous doctors Mr. Li Peiwen of China-Japan Friendship Hospital believes that there are various TCM syndromes of lung cancer, and patients complicated with massive hemoptysis, infection, DIC and respiratory acidosis are often related to lung yin deficiency. The later the course of disease, the more lung yin deficiency will appear. Therefore, it is of great significance to prevent and treat Yin deficiency syndrome. There are many similar symptoms between lung cancer and diseases such as heartburn and cough in TCM, but there are many similarities between lung fistula in TCM and advanced lung cancer. "Pulmonary fistula" caused by deficiency-heat is often a serious disease. Lung qi deficiency, body fluid deficiency and malnutrition lead to "lung leaf withered". There are many reasons for lung yin deficiency. For example: ① the patient has always been a constitution of lung and kidney yin deficiency, and the symptoms of yin deficiency are aggravated after suffering from lung cancer; ② During the surgical resection of lung cancer, too much body fluid was lost, and it was not replenished in time after operation; (3) radiotherapy? Quot heat poison hurts yin "; ④ In the treatment of malignant hydrops, a large amount of diuretics were given, resulting in loss of body fluids or hypokalemia; ⑤ Bleomycin, Pingyangmycin, high-dose cyclophosphamide chemotherapy or toxicity superposition with radiotherapy cause pulmonary fibrosis. To prevent and treat the occurrence of lung yin deficiency, the commonly used prescriptions are: Baihe Gujin Decoction and Qingzao Jiufei Decoction. The basic prescription is: ginseng, asparagus, radix rehmanniae, radix scrophulariae, lily, radix paeoniae alba, almond, platycodon grandiflorum, Fritillaria, mulberry leaf, loquat leaf, houttuynia cordata and scutellaria barbata. This recipe can nourish yin and replenish qi, relieve cough and dissipate stagnation. Modern research has the functions of improving immune function, inhibiting tumor and relieving cough. Lily, for example, not only has the functions of invigorating qi, clearing heart, moistening lung and relieving cough, but also contains colchicine, which can inhibit the mitosis of tumor cells. Carotene and vitamin C contained in lily are also related to tumor inhibition. Modern research has confirmed that the drug can enhance the immune function of monocytes and resist aging. Asparagus can nourish yin, promote fluid production, relieve cough and stop bleeding, and its tumor inhibition rate in vitro can reach 44%. Some people think that asparagus compound has obvious inhibitory effect on animal lung squamous cell carcinoma and adenocarcinoma, which can reduce lung metastasis and improve lymphocyte transformation and nk cell activity. Loquat leaf, houttuynia cordata, Scutellaria barbata and Fritillaria are also important lung meridian drugs for softening and resolving hard mass. In addition, other drugs also have the functions of relieving cough, moistening lung, stopping bleeding and clearing heat, and often achieve obvious clinical effects. (4) Acupuncture therapy 1. The main acupuncture points are Fengmen, Shu Fei, Xinshu, Tianquan, Gaojia, Zhongfu, Chize, abdomen, pain and cancer. Select three acupoints: Legue, Neiguan and Zusanli. Ear points include upper lung, lower lung, heart, large intestine, adrenal gland, endocrine, nose, pharynx and chest. Tonifying and reducing simultaneously, daily 1 time, and keeping needles for 20 ~ 30 minutes each time. Suitable for all stages of lung cancer. Acupuncture can be combined with decoction and medicine at the same time. 2. Acupuncture and acupoint injection acupuncture Baihui, Neiguan, chest area, Fengmen, Shu Fei, Dingchuan, Fenglongtu, Zusanli and Dazhui were injected with 20% ~ 50% Placenta Injection (14 ~ 16 ml) respectively. 1 once a day or every other day, continuous treatment 15 days is a course of treatment, rest for 3 ~ 5 days, and then start the next course of treatment. It is suitable for patients with advanced pain of lung cancer and other malignant tumors. (5) topical medicine 1. 20 grams of Rhizoma Kaempferiae, Olibanum, Myrrha, Curcuma Rhizome, Gardenia, Radix Angelicae Dahuricae and Scutellariae Radix, 20 grams of fennel, Flos Caryophylli, Radix Paeoniae Rubra, Radix Aucklandiae and Cortex Phellodendri, and 20 grams of castor bean. Apply * * * to fine powder, mix it with egg white and apply it to Rugen point, and change the dressing every 6 hours. Suitable for patients with lung cancer pain. 2. Venenum Bufonis Xiao Zhong ointment is composed of more than 20 kinds of Chinese medicines, such as Venenum Bufonis, Asari, Radix Aconiti, Herba Hedyotidis Diffusae, Carthami Flos, Folium Isatidis, etc. It is a traditional Chinese medicine plaster made of rubber zinc oxide as matrix. Before use, clean and dry the skin, then stick the plaster on the painful part and change the dressing every 24 hours. Suitable for patients with lung cancer pain. 3. Take Camphor, Ferula, Clove, Rhizoma Kaempferiae, Rhizoma Paridis and Garcinia, grind into powder, and seal for later use. When in use, the medicine is sprinkled on the adhesive tape in turn, applied to the painful part of the patient's lung cancer, and then applied with a hot towel at about 60℃ for 30 minutes. Hot compress 3 times a day, and change the dressing every 5 ~ 7 days. (6) dietotherapy 1. The lung qi injury after postoperative diet surgery should be mainly based on invigorating qi and nourishing blood. Choose almond dew, yam powder, fresh Chinese cabbage, white radish, winter melon skin, winter melon seeds, hawthorn, lotus root and other foods. 2. Dietetic therapy for lung yin is heavier during radiotherapy, so it is advisable to nourish yin and replenish blood. Choose fresh vegetables and fruits, such as spinach, almonds, walnuts, loquat fruits and medlar fruits. 3. During chemotherapy, diet chemotherapy, both qi and blood injuries, should be based on invigorating qi and blood. Choose soft-shelled turtle, soft-shelled turtle, fresh carp, tremella, mushrooms, bird's nest, sunflower, hawthorn, ginkgo, etc. Modern research on the pathogenesis of lung cancer with yang deficiency 1. The diagnosis of lung cancer is more common in tongue picture, meridian and acupoint diagnosis. Shi Bianzhen and others have proved through a lot of clinical observation and tongue diagnosis research that lung cancer is characterized by purple tongue coating, fat tongue, cracks on the face, tooth marks on the edge, swollen sublingual collaterals and thick and greasy tongue coating. Professor Shao Mengyang observed the curative effect of 30 cases, and found that the tongue picture of those with better curative effect changed obviously, suggesting that the tongue picture is not only of great value for early diagnosis of this disease, but also of reference significance for curative effect evaluation and prognosis judgment of this disease. Clinically, the author also observed that in patients with lung cancer, the early tongue is pale, the coating is white and greasy, the middle and late tongue is purple and dark, the tongue is fat, there are teeth marks on the side, the sublingual collaterals are large and swollen, the coating is thick and greasy, and the patient's nose is often purple, which is the symptom of qi stagnation and blood stasis in tumor patients. After the treatment of warming yang, benefiting qi, promoting blood circulation and removing blood stasis, this performance has improved and the condition has been controlled, otherwise. 2. Professor Liu Jiaxiang believes that the formation of lung cancer is mainly due to the deficiency of vital qi, the imbalance of Yin and Yang, and the evil of six evils can take advantage of it, and the evil spirits stay in the lung, leading to lung qi stagnation and blood stasis, and the body fluid does not disperse, leading to phlegm, phlegm and blood stasis, which will become a mass over time. It can be seen that lung cancer is caused by deficiency, and it is caused by deficiency. Deficiency is the root of disease, but it is the standard of disease. Chinese medicine has always been respected? Quot treatment must seek its root ",what's more, qi deficiency in the late stage of lung cancer is particularly obvious. Therefore, the treatment of advanced lung cancer should be based on the principle of strengthening the body resistance and eliminating pathogenic factors. Through comparative observation and research, it is considered that the effects of nourishing yin and promoting fluid production and nourishing qi and warming yang in the treatment of advanced lung cancer are as follows: ① prolonging the survival time of patients; ② Relieve and stabilize the focus; ③ Improve the quality of life of patients; ④ Improve the immune function of the body. Through comparative observation, it shows that this therapy is a good method to treat advanced primary lung adenocarcinoma. 3. Professor Yu believes that the pathogenesis of lung cancer in Chinese medicine academic circles is mostly unified under the principle of insufficient righteousness and evil. There are different opinions about the specific connotation of insufficient positive energy. Many people say that qi deficiency and yin deficiency, but there is no report about yang deficiency. Professor Yu's clinical research on the treatment of primary bronchial lung cancer by warming method has achieved certain results. He believes that yang deficiency is the key to the deficiency of positive energy in this disease, which is directly related to the emergence and development of pathogenic excess. This is because: first, among the four elements of qi, blood, yin and yang, Yang is in a dominant position, that is, Su Wen's statement that anger reaches heaven: "If Yang is in heaven, it will be premature if Yang is out of position." Secondly, from the distribution of onset age, it increases after 40 years old, especially after 50 ~ 60 years old. Furthermore, judging from the pathogenic factors of this disease, the occurrence of tumor is mainly due to stagnation of qi and blood, while the lung governs qi, regulates waterways and transports body fluids. Therefore, the reality of lung cancer is related to phlegm besides blood stasis. "Su Wen jumps over the economy"? Quot "Blood-like people prefer warmth to cold. Cold makes them cry but can't flow. It can be seen that yang deficiency leads to yin excess and yin excess leads to cold, which is the main internal cause of lung cancer. Therefore, the clinical application of wentongzhi has achieved good results. Its basic prescription is: aconite root120g, cowherb seed 30g, astragalus root 30g, cassia twig15g and zedoary rhizome12g. Combined with self-made compound Sansheng injection (composed of raw aconite, raw aconite, raw Nanxing, etc.). ), 5 ~ 10~20ml intramuscular injection twice a day, or 10~20ml intravenous injection with 50% GS400 ml, or 50 ~ 70 ml intravenous infusion with 10% GS 50~70ml. For lung cancer patients, some have no symptoms of yang deficiency and yin excess, and some even have clinical manifestations of yin deficiency. Yu believes that this is the complexity of lung cancer. He believes that yang deficiency is the main pathogenesis, which can be manifested as chills and cold limbs caused by insufficient warmth, or cough, phlegm and saliva caused by yang deficiency, constipation caused by yang deficiency and yin deficiency, red tongue and little fur. And may involve chest pain, purple tongue and other secondary onset or blood loss control. Therefore, the author's treatment is mainly based on syndrome differentiation, that is, lung cancer is the basis for diagnosis of yang deficiency, and at the same time, through the combination of disease differentiation and syndrome differentiation, different manifestations of yang deficiency in different lung cancer patients are treated by syndrome differentiation. The medicine of warming yang and dispelling cold focuses on supernormal, and the combination of decoction and injection has obvious curative effect. So far, there have been no obvious complications such as drying up the yin or accelerating the spread of cancer, and there have been no unintentional toxic and side effects such as liver and kidney function damage. Through modern related research, it is confirmed that the fundamental pathogenesis of lung cancer is "yang deficiency", which guides the correctness of the main prescription of lung cancer. Let people innovate boldly in practical application, combine disease differentiation with syndrome differentiation, and combine traditional Chinese and western medicine to make contributions to the breakthrough of lung cancer treatment. (eight) the combination of traditional Chinese medicine with radiotherapy and chemotherapy is harmful to human body. According to the four diagnoses and reference, it is considered that radiotherapy and chemotherapy belong to the category of "heat toxicity" and are easy to hurt yin, so the treatment should be nourishing yin and blood, clearing away heat and detoxifying. 1. Chemotherapy mainly focuses on nourishing blood and activating blood, supplemented by invigorating spleen and regulating stomach. Radix Angelicae Sinensis 9g, Radix Paeoniae Rubra 9g, Rhizoma Chuanxiong 9g, Radix Rehmanniae 9g, Caulis Spatholobi 15g, Trichosanthis Radix 9g, Fructus Ligustri Lucidi 15g, Radix Codonopsis 9g, Atractylodis Macrocephalae 9g, Coicis Semen 15g, Radix Astragali 30g, and five Chinese dates. 2. Nourishing blood and promoting blood circulation during radiotherapy, supplemented by nourishing yin and regulating stomach. Radix Angelicae Sinensis 9g, Radix Paeoniae Rubra 9g, Rhizoma Chuanxiong 9g, Radix Rehmanniae 9g, Semen Lablab Album 9g, Scutellariae Radix 6g, Rhizoma Imperatae 15g, Fructus Trichosanthis 15g, Radix Ophiopogonis 9g, Pericarpium Citri Tangerinae 9g and Trichosanthes Radix 9g. 3. During the rest period of radiotherapy and chemotherapy and after radiotherapy and chemotherapy, it is advisable to treat lung cancer with traditional Chinese medicine.