Systemic symptoms: fatigue and weakness is one of the late symptoms of liver cirrhosis. The late symptoms of liver cirrhosis are mostly dry and rough skin and dull complexion.

Symptoms of digestive tract: loss of appetite is the most common symptom in the late stage of liver cirrhosis, sometimes accompanied by nausea and vomiting. Generally, it is characterized by poor nutritional status, obvious loss of appetite, epigastric discomfort, fullness, nausea and even vomiting after eating, poor tolerance to fat and protein in the late stage of liver cirrhosis, and eating greasy food is easy to cause diarrhea. Patients with liver cirrhosis feel unbearable abdominal distension due to ascites and gastrointestinal pneumatosis, and toxic abdominal distension may occur in the late stage.

Portal hypertension: manifested as esophageal varices, splenomegaly and ascites, especially esophageal varices. Due to the thin wall of varicose veins, it is easy to rupture and lead to massive bleeding in the digestive tract.

Formation of ascites due to liver cirrhosis: Abdominal distension often occurs before ascites occurs in the late stage of liver cirrhosis. A lot of water makes the abdomen swell, and the abdominal wall is tight and bright, like the abdomen of a frog. Patients have difficulty walking, and sometimes the diaphragm is obviously elevated, leading to respiratory hernia and umbilical hernia.

Bleeding tendency and anemia: nosebleed, gingival bleeding, skin ecchymosis, gastrointestinal mucosal erosion and bleeding, nosebleed, hematemesis and black stool are common in the late stage of liver cirrhosis, and women often have symptoms such as menorrhagia.

Endocrine disorder: In the late stage of liver cirrhosis, the function of the liver declines more obviously, which directly leads to the decrease of estrogen inactivation, the increase of estrogen secretion, the large amount of estrogen in the blood and the inhibition of androgen.

A series of complications caused by late cirrhosis seriously threaten human health. Therefore, experts from the Cell Biotherapy Center of Fuzhou Stem Cell Center pointed out that understanding the early symptoms of liver cirrhosis has a positive effect on the early detection and treatment of liver cirrhosis. Patients with liver diseases such as hepatitis B and fatty liver should pay attention to their own physical changes and seek medical treatment immediately if they feel uncomfortable.

As a brand hospital, the Cell Therapy Center of the 322nd Hospital of the People's Liberation Army provides the most advanced stem cell transplantation technology, which can effectively treat various brain diseases, Parkinson's disease, diabetic complications, liver cirrhosis, liver fibrosis and other traditional "intractable diseases".