1, the malignant transformation of squamous epithelial cells caused by long-term lip mucosal ulcer is relatively rare in clinic, and if the cauliflower-like process does not suddenly appear and expand rapidly in the past two years, the possibility of highly malignant canceration is not high, because squamous epithelial cell carcinoma will develop to a very serious degree in a year or so without special treatment.

2, cytological pathological examination does not have to do "biopsy", if the patient is particularly afraid of biopsy, you can also do pathological examination by scraping the cells obtained from the surface of the ulcer, but such examination is not as reliable as biopsy, but if the ulcer has become malignant, the probability of detection is also high.

3. The affiliated hospital of medical university in the local provincial capital city is usually the hospital with the strongest comprehensive strength in all provinces, so the examination and treatment of intractable lip ulcer should not be a problem. Therefore, it is suggested that patients should be examined as soon as possible and treated in time, because long-term ulcers are indeed one of the causes of malignant transformation, and once ulcers become malignant, their treatment is much more difficult and complicated than intractable ulcers.

4. Since the traditional Chinese medicine treatment currently used by patients is ineffective, it should be stopped, otherwise it may lead to the delay of illness.

For reference only.