Artificial substances include silicone rubber, expansive materials, liquid silicone rubber, etc. Silicone rubber is the most commonly used material in nasal surgery at present. It will not deteriorate or be absorbed, and it can be shaped more accurately than expanded materials. However, some people's skin is thin, which may leak out. In rare cases, there may be side effects due to excessive cyst formation. This material is mainly used when the skin is thick and the nose is low. Compared with silicone rubber, the swelling material has a softer touch. This soft touch comes from the fine porous structure of the swelling material, but it may collapse with the passage of time after transplantation, which is its disadvantage. This material is suitable for people with thin skin. Liquid silica gel is a kind of material, which is occasionally used to replace septal cartilage when bridging the bridge of the nose or lengthening the nasal septum.
For autologous tissue, cartilage and dermal fat such as auricular cartilage, alar cartilage and nasal septum cartilage can be used. Cartilage is generally used to shape the tip of the nose. In addition, the nasal septal cartilage without twists and turns is mainly used to erect the bridge of the nose or extend the length of the nose. Another method of autologous tissue transplantation is "dermal-fat transplantation", that is, the method of cutting dermis and fat from buttocks, armpits and crotch for transplantation, which is generally used for noses with side effects or noses with thin skin. The disadvantage of this method is that cutting off the dermal fat will leave scars, which are difficult to completely remove in the later stage, and it is also difficult to make a thin and pointed nose, but the advantage is that it is soft to the touch and very close to the original skin. Dermal tissue, the skin donated to the "tissue bank" has been treated to eliminate pathogenicity and antigenicity and make it suitable for transplantation, that is, dermal tissue that we can apply mainly replaces cartilage in the shape of the tip of the nose, giving people a softer feeling than cartilage.