The main reason is the obstruction of ureteropelvic junction, which is often due to the fact that the muscle cells in this area are separated by a large number of collagen fibers and lose their normal arrangement, which can not effectively transmit the electrical activity from pacing cells and block the transmission of normal peristalsis.
Suggestion:
1. Conservative therapy
(1) Hydronephrosis is mild, the disease progresses slowly, and the renal function has reached a balanced and stable state, which can be observed, but the progress of hydronephrosis should be checked regularly.
(2) Obstruction that can be relieved by itself, such as physiological hydronephrosis in pregnant women.
2. Surgical therapy
(1) surgical indications: hydronephrosis is aggravated, with obvious clinical symptoms, decreased renal function, clear reasons for obstruction, and complications, so surgery should be performed.
(2) the principle of surgical treatment:
① Clear the obstructive diseases that cause hydronephrosis, such as taking stones; Relieve the compression of fibrous cord or vagus nerve blood vessels; Prostatic hyperplasia can be excised or excised.
② Severe hydronephrosis leads to complete loss of renal function or serious infection and pus accumulation, but the contralateral renal function is good and nephrectomy is feasible.
③ The renal function of the affected side is very poor due to hydronephrosis. Nephrostomy should be performed before further treatment of obstruction caused by other diseases or even uremic hydronephrosis in the contralateral kidney.
④ Attention should be paid to bilateral hydronephrosis to eliminate the cause of lower urinary tract obstruction. Generally, the patient with good condition is treated first, and then the patient with serious condition is treated after the situation improves. Usually, unilateral nephrostomy should be performed first.
⑤ Obstruction of infundibular part of hydronephrosis is mostly caused by stones. If there are no clinical symptoms, surgery is generally not needed.
Life care:
⑥ Principles of plastic surgery: Pay attention to the normal anatomical relationship between kidney and ureter, and keep the smooth drainage of kidney and ureter. When anastomosing at the lowest part of renal pelvis, the anastomosis should be prevented from varus, and it should be funnel-shaped after suture. When repairing, cut off the adhesion scar of fibrous tissue as much as possible to avoid hurting blood supply, and properly keep the surrounding adipose tissue to cover the operation field.