This product is the "ace" antibiotic with the strongest effect on Pseudomonas aeruginosa among similar drugs, with 2-4 times stronger antibacterial activity than similar drugs; it is effective against most enzyme-producing and non-enzyme-producing Gram-positive bacteria. It is effective against cocci and negative bacilli and is a super-broad-spectrum antibiotic. It has extensive synergistic effects and is convenient for clinical symptomatic combination use. Foreign clinical studies have shown that this project has good efficacy and its side effects are smaller than those of other penicillins.
General clinical trials and three comparative clinical trials were conducted in 450 institutions in Japan, with a total of 2310 cases. When used in sepsis and infective endocarditis, Staphylococcus and Streptococcus were The effective rate for septicemia and infective endocarditis caused by genus, pneumococcus, enterococcus, coliform, etc. is 61.5% (16/26); when used in surgical and orthopedic infections, it is effective against Staphylococcus spp., Streptococcus spp. The effective rate is 81.4% (70/86) for surface secondary infections such as trauma and surgical wounds such as coliforms, Bacteroides, etc.; when applied to respiratory infections, it is effective against Staphylococcus, Streptococcus, Pneumococcus, Respiratory infections (pharyngitis, acute bronchitis, tonsillitis, chronic bronchitis, bronchiectasis infections, secondary infections of chronic respiratory diseases, pneumonia, pulmonary suppuration) caused by enterococci, Haemophilus influenzae, etc. The effective rate is 83.4% (373/447); when applied to hepatobiliary tract infections, the effective rate is 80.0% (24/30) against cholecystitis and cholangitis caused by Streptococcus, Enterococcus, Coliform, etc.; when applied to When used for peritonitis, the effective rate against Streptococcus, Enterococcus, Coliform, Bacteroidetes, etc. is 90.0% (18/20); when used for otitis media and pararhinitis, the effective rate against Staphylococcus, Streptococcus, The effective rate for treating otitis media and pararhinitis due to enterococci, pneumococci, coliforms, Haemophilus influenzae, etc. is 63.6% (117/184); when applied to gnatitis, it is effective against Staphylococcus, Streptococcus, pneumococcus, The effective rate for Haemophilus influenzae gnatitis is 90.0% (18/20).