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How to treat cicatricial alopecia?
How to treat cicatricial alopecia?

How to treat cicatricial alopecia? There are many kinds of hair loss. Scar alopecia is very common in our life. Many of us suffer from cicatricial alopecia, which often has a great impact on our lives. Let's see how to treat cicatricial alopecia.

How to treat cicatricial alopecia 1 At present, medical technology is very developed, and there are many methods to treat cicatricial alopecia. We must treat cicatricial alopecia as soon as possible. At present, cicatricial alopecia can be treated by drugs, external use, physics, laser and other methods. There are two common drugs, one is steroid hormone, and the other is cyclosporine. These two drugs are very effective in the treatment of cicatricial alopecia, so we must treat them as soon as possible.

Steroid hormones, including oral or intramuscular glucocorticoid, are very effective in treating cicatricial alopecia, but long-term use of glucocorticoid will have great side effects and do great harm to patients' health. Therefore, people can't use glucocorticoid for a long time. At the same time, once these drugs are stopped, they will recur. Therefore, this drug treatment can only temporarily alleviate the development of the disease and control the symptoms of the disease, but can not achieve the effect of complete cure.

We all know that there are many ways to treat cicatricial alopecia. Usually, patients will be treated with drugs. In addition to the above drugs, there are thymosin drugs that can treat this disease, but the side effects of drug treatment are relatively large. Everyone must take medicine under the guidance of a doctor when treating, and never take medicine privately, otherwise it will be very harmful.

How to treat cicatricial alopecia? 2 1, direct excision and suture

For cicatricial alopecia with long and narrow head, local excision and direct suture of scalp can be used. Young people have thin scalp and elasticity. Even if the scar is slightly larger, it can sometimes be sutured directly after excision.

If this method can't completely remove the scar at one time, you can take multiple surgical excision and suture by stages. After the scar is reduced to a certain extent, the hairless area can be completely covered by combing the hair.

2. scalp flap transfer and repair

This method is suitable for cicatricial alopecia with large head area. To treat cicatricial alopecia, a local scalp flap can be designed according to the specific conditions of scar area and hair-containing parts, and the cicatricial alopecia area can be covered by pushing and rotating. It is generally believed that cicatricial alopecia accounts for 1/4 ~ 1/3 of scalp hair area and can be repaired by scalp flap transfer.

3. Scalp dilator method

This type of treatment divides cicatricial alopecia into two stages:

In the first stage of the operation, the expansion sac was first buried under the aponeurosis of the hairy scalp cap. After suture removal after operation, sterile saline can be injected into the expansion sac from the injection jug, and the injection amount is 10 ~ 15% of the expansion sac (generally 10 ~ 15 ml), once every 3 ~ 7 days until the expansion sac is filled and properly expanded.

The second operation is to take out the expansion sac, remove the scar, design the expanded scalp with hair as a flap, repair the wound by pushing and turning, and eliminate the hair loss area. After 3 months to half a year, hair growth will be normal. For a large area of hair loss area, if it is difficult to repair all the hair loss areas by one expansion, the expander can be buried again for secondary repair, and the scalp hair loss area can be repaired 1/2 ~ 2/3.

How to treat cicatricial alopecia 3? Comprehensive treatment of cicatricial alopecia

Drug therapy:

① Glucocorticoid: Oral or intramuscular injection is often effective, but long-term treatment has great side effects, and it will recur after drug withdrawal. It is not suitable for routine treatment, and it is only used for alopecia totalis, alopecia universalis and alopecia with rapid progress, and the short-term effect is obvious after use. For example, prednisone 20 ~ 40 mg/d, taken orally several times, 1 ~ 2 months later, reduced according to the condition. Low dose (10mg/d) lasts for 6 months or is combined with other drugs (such as minoxidil). Dessert-misoprostol, methylprednisolone or diprospan can be selected according to the situation.

② Cyclosporine: 6mg/kg orally every day, taking effect for 2-4 weeks, and it can recur after stopping taking medicine. Pay attention to its hypertension and nephrotoxic side effects.

③ Thymosin: The mechanism of treating alopecia areata may be to stimulate inhibitory cytotoxic T cells and correct abnormal T cell-mediated immunity of alopecia areata. 50mg/ time, intramuscular injection, every other day 1 time, lasting 1 month.

④ Others: Isopropylinosine, dapsone, minoxidil and thyroxine can be used as appropriate.

External treatment: most of them are irritants, causing local moderate contact inflammation, making local congestion and promoting hair regeneration.

① Glucocorticoid preparations such as 0.05% betamethasone cream or 0. 1% triamcinolone acetonide cream combined with 5% minoxidil are more effective. You can also inject a small dose of triamcinolone acetonide suspension (2.5 ~ 10 mg/ml) into the skin lesions, each time 0. 1ml, once a week, 1 0 times as a course of treatment.

② Anthracene ointment and 0.5% ~ 1% anthracene cream were applied externally for 30min every day, and then the action time was gradually prolonged, and hair regrowth occurred within 3 months. Alternating use of 5% chlorhexidine cream (night) and 5% minoxidil (day) has synergistic effect on most refractory cases.

③0.002% nitrogen mustard hydrochloride solution, 5% minoxidil (minoxidil) solution, dibutylsqualene ester and diphenylpropenone can all be selected as appropriate.

④ Vitamin E 5 ~ 75 mg each time, atropine 0. 1mg each time, anisodamine (654-2), etc. It can be injected intradermally locally, every week 1 ~ 2 times, with 8 ~ 10 times as a course of treatment.

Physical therapy:

① Freezing: adopt low-temperature liquid nitrogen freezing method, 1 time per week, usually 1 ~ 2 times, and it will take effect.

② Laser: He-Ne laser irradiation, each lesion 10min, 1 time every day, and 1 time after 6 times.

③ Photochemical therapy (PUVA): It may play a role by inhibiting the local immune attack of Langerhans cells on hair follicles. 1% 8- methoxysarin ointment or solution for external use, or 8-MOP(0.6mg/kg)65438+UVA irradiation for 0-2 hours, 2-3 times/week, and gradually increase the light quantity. The curative effect on alopecia universalis is not good.

④ Hematoporphyrin (Hp) and UVA: 0.5% HP was used externally, and UVA was irradiated locally 2 hours later, with a dose of 4J/cm2 each time, three times a week, with a total dose of 96 ~ 120J/cm2.

⑤ Other therapies: such as ultraviolet irradiation, lighting, massage and wax therapy. , you can choose.

Psychotherapy: find the cause, give corresponding treatment and reduce the mental burden. You can wear a wig to relieve mental stress. For those with obvious mental factors, sedatives such as diazepam and bromine are given. Vitamin B 1, B6, oryzanol or cystine (50 mg/time, 2-3 times /d) were given.

Prognosis: Patients with lesions less than 25% have a high self-healing rate. The wider the lesion, the worse the prognosis. The factors influencing the prognosis are: concomitant atopic dermatitis, early onset, widespread alopecia, crawling alopecia, 5 years' course of disease and nail malnutrition.