Rheumatoid arthritis is a chronic systemic autoimmune disease with joint lesions as the main factor. It is generally believed that this disease is an autoimmune disease with both abnormal cellular immunity and humoral immunity. The causes of immune abnormalities may be related to the following three factors: ① infection, ② family inheritance and ③ endocrine disorders. The onset of rheumatoid arthritis is slow. At the beginning of the disease, there may be pioneer symptoms such as fatigue, loss of appetite, weight loss, low fever, numbness and tingling in hands and feet, and then joint pain, swelling and joint stiffness. The swelling of the proximal knuckle (that is, the knuckle close to the palm) can make the finger spindle-shaped, which is most obvious in the morning and relieved after exercise (this phenomenon is called morning stiffness). The joints involved are mainly the small joints of both hands (especially the proximal interphalangeal joints and metacarpophalangeal joints), wrist, knee and foot joints, elbow, shoulder, hip and ankle can also be involved. Only one or two joints may be involved in the initial stage of the disease, and then symmetrical polyarthritis will develop. In the late stage of the disease, the joints are deformed, stiff and limited in function, and the muscles near the joints are atrophied. Chronic skin ulcer, myositis, pericarditis, neuropathy, myocardial infarction, valve disease, granulomatous pneumonia or extensive pulmonary interstitial fibrosis may also occur. I don't know how serious your family's illness is, but I still suggest you take your family to the hospital for a detailed examination. After all, rheumatoid disease is not a minor illness, so don't delay. The condition is getting worse. If rheumatoid disease is treated as soon as possible, its recovery will mostly be better. Acute attack is better than slow attack, and male is better than female. Only a few joints are involved, but the systemic symptoms are mild, or the joints are asymmetrical, the course of disease is often short, and about 10% ~ 20% patients are disabled due to untimely treatment. This disease does not directly lead to death, but serious advanced cases can die of secondary infection. Therefore, rheumatoid arthritis should be treated as soon as possible without delay. Once the best treatment period is missed, rheumatoid arthritis will become an incurable disease. I suggest you go to Zhongan Hospital. They are the most authoritative in treating rheumatoid diseases. There are 20 branches in China and Dongying. Please go and have a look. I hope my answer can help you! ! Their address in Dongying is opposite to the Central Hospital at No.30 Jinan Road, Dongying District, Dongying City, Shandong Province. Their hospitals can also be found online. You can Baidu, and get to know it first! ! Hmm. How interesting