If you don't need to be hospitalized, you can give 1. Antihistamines: mainly include H 1 receptor antagonists and H2 receptor antagonists. Various antihistamines have different antihistamines and other pharmacological effects. For example, cyproheptadine is effective for cold urticaria, and Antaile is effective for hot urticaria. For intractable urticaria, H 1 and H2 receptor antagonists can be combined to improve the curative effect. 2. Adrenal cortical hormone: used in acute severe or intractable cases, such as anaphylactic shock, serous urticaria, stress urticaria, etc. Hydrocortisone 100~200MG is added into 5% glucose solution for intravenous drip, or 30~40MG of prednisone is taken orally. This therapy is generally not suitable for long-term application. 3. Antibiotics: Those who are infected can choose appropriate antibiotics, especially urticaria caused by obvious or concealed gastrointestinal infections. 4. Drugs that reduce vascular wall permeability: such as vitamin C, vitamin P, calcium, etc. Often used with antihistamines. 5. Sympathomimetic drugs: mainly used for severe acute urticaria's disease, especially when there is anaphylactic shock or laryngeal edema. Subcutaneous injection of 0. 1% epinephrine 0.5~ 1 ml. In severe cases, it can be injected again every 20 to 30 minutes.