On June 2 1925 and 2 1 day, workers in Hong Kong and Guangzhou also went on strike to support the striking workers in Shanghai, and the workers left their jobs and returned to Guangzhou. 1On June 23rd, 925, people from all walks of life in Guangdong held a conference in the eastern suburbs to denounce the May 30th massacre made by imperialism in Shanghai, and then held a demonstration. Chen Yannian and Zhou Enlai, the main leaders of Guangdong District Committee, attended the military parade. At 2: 00 p.m.15, the procession arrived in Shaji, turned into Cai Lan Street in an orderly way, and continued to March in Shaji and Xidi in an orderly way. At 2: 40, when students from Lingnan University, Wei Kun Women's Normal School, Sacred Heart College, Zhixin and Guangzhou No.2 Middle School and Huangpu Military Academy marched to Shaji, a foreigner from the Victoria Hotel (now Shengli Hotel) next to Shamian West Bridge first shot at the parade. The British and French troops at the foot of Shamian West Bridge, which was already on alert, immediately seized the machine gun and opened fire on Shaji. The procession could not escape and killed many people on the spot. In order to avoid the deterioration of the situation, China soldiers and military school students who took part in the parade obeyed the discipline and did not fight back.

Immediately after the tragedy, the National Government lodged the most serious protest with the British, French and Portuguese consuls in Guangzhou in the name of Governor Hu of Guangdong, and lodged a second serious protest with the consuls of various countries on 26th: (1) The countries concerned in this case sent officials to apologize to the Guangdong revolutionary government; (two) the punishment of staff related to the case; (3) Except for two communication ships, all the warships of the countries concerned in Guangdong withdrew; (4) Shamian Concession was taken over by Guangdong Revolutionary Government; (5) Compensation for pensions for casualties. He also asked for the return of the Shamian Concession and compensation for the losses of the people killed in China, but was arbitrarily rejected by the Guangdong, British and French consuls.

On the 29th, many groups in Guangzhou called for breaking off economic ties with Britain. On the same day, 250,000 workers in Hong Kong went on strike, and130,000 people evacuated to Guangzhou one after another.