Although there are many similarities between domestic botulinum toxin and imported botulinum toxin, there are still subtle differences, mainly in purification methods, drug purity and dispersion. The imported botulinum toxin uses human albumin, and the domestic botulinum toxin uses pig gelatin. Pig gelatin is a heterogeneous protein, which is easy to cause immune response. At the same time, imported botulinum toxin adopts vacuum drying method (liquid-solid), and domestic botulinum toxin adopts freeze drying method (solid-solid). The dispersion of imported botulinum toxin after injection is 5 mm smaller (radius); However, the dispersion of domestic injection is larger (radius)10 mm.
In most cases, when precise injection is needed, such as the treatment of frown lines, the smaller the dispersion, the more obvious the advantages, and the lower the incidence of individualized treatment and adverse reactions (in addition to face-lifting, botulinum toxin can also be used to remove wrinkles). In view of these points, the comprehensive evaluation of the efficacy and safety of imported botulinum toxin injection is better than that of domestic botulinum toxin.