Dog vaginal hyperplasia is a kind of external reproductive tract disease in which the bitch's vaginal mucosa is excessively edema and hyperplasia, and protrudes backward to the inside or outside of the vulva. It often occurs in pre-estrus and estrus, and is more common in bitches who are in estrus for the first time or have given birth to one or two children. At this time, the secretion of estrogen increased sharply, and the vaginal mucosa overreacted to estrogen, resulting in congestion, edema and excessive proliferation. Some medium and large puppies are more frequent, which may be related to heredity. Mild hyperplasia can be treated with hormones, and severe irreversible hyperplasia prolapse and ulcer necrosis that affect normal breeding need surgical treatment.

I. Case introduction

The dog is 8 months old and in good mental condition. The chief complaint is that the dog/kloc-started estrus 0/0 days ago. Three days ago, the labia became swollen and congested, licking the labia frequently from time to time, and then being scolded, squatting to pee and lying restless. When the dog is lying on the ground, the vulva opens, revealing a red fleshy growth, which is spherical and swollen. The growth is 5*6 cm in size, with smooth and moist surface, pink texture and softness (Figure 2). In recent days, the amount of drinking water has increased first and then decreased, and urination is normal.

Figure 1 Good mental state.

Fig. 2 The proliferation size is 5*6 cm, the surface is smooth and moist, pink and soft.

Second, diagnosis and treatment.

To reduce vomiting and protect heart function before anesthesia, atropine sulfate 0. 1 ~ 0.5 mg/kg body weight was injected intramuscularly, and 846 compound anesthetic 0. 1 ~ 0. 15 ml/kg body weight was injected intramuscularly 30 minutes later. The abdomen is horizontal and Baoding, and the hindquarters are raised. The tail is tied with a rope and bent forward to be fixed. Gauze piece can be inserted into anus to prevent fecal contamination. Use 0. 1% bromogeramine solution to clean perineum, shave hair, rinse vagina, genital tract, urogenital vestibule and growth, and then cover the wound towel. In order to identify and protect urethra, a catheter was inserted before operation.

Fig. 3 Cleaning, shaving and routine disinfection of perineum.

Fig. 4 Preoperative catheter insertion

First, open the surgical channel for surgery. Two hemostatic forceps were used to clamp both sides of the vulva, and the junction of the vulva was cut to the level of the vaginal dorsal side wall to avoid tissue hyperplasia and eversion, and the vagina, vestibule and hyperplasia were fully exposed. It was found that the thick blood vessels were ligated with silk thread. After determining the position of the implant, a transverse incision was made in the dorsal mucosa (as deep as possible) of the implant base, then it was turned to cut in front of the external orifice of the compound urethra, and then the hyperplastic vaginal mucosa was passively peeled back. When stripping, touch the catheter and master the separation depth to avoid damaging the urethra. After 8-shaped ligation at the base of the grower, all of them were removed. After thorough hemostasis, the surgical site was thoroughly washed and disinfected with 0.2% nitrofurazone solution and sprayed with streptomycin. Continuous suture of vaginal abdominal wall with No.4 silk thread, continuous suture of combined incision on vulva, and suture of vulva skin with No.7 silk thread nodule. Take off the wound towel and disinfect it with iodine. Intramuscular injection of phenylethylamine 2 mL. Sue was used to wake up after the operation.

Fig. 5 During the operation.

After 3 days of fasting, only sugar and saline were gradually supplied. Ampicillin 0.5 g, antongding 2 mL and vitamin K 1 10 mg were injected intramuscularly every time, twice a day for the first two days and 1 time every day after the third day for 4 days. Supplementing energy and nutrition at the same time, adjusting electrolyte balance, vitamin C 0.5 g, vitamin B6 200 mg, inosine 100 mg, ATP 20 mg, cytochrome C 100 IU, intravenous infusion 10% glucose solution 100 mL, and compound sodium chloride/kloc. 10% potassium chloride 1 ml, 18- amino acid 30 ml intravenous injection. In addition, in order to prevent postoperative local anaerobic infection, 0.5% metronidazole 100 mL can be injected intravenously, 1 time, 1 time daily for 3 days.

Fig. 6 Growth after resection

Third, diagnosis and treatment experience

This disease should be differentiated from vaginal tumor and vaginal prolapse. Canine vaginal hyperplasia can be distinguished from vaginal tumor by biopsy: vaginal hyperplasia, with a large number of keratinocytes and stratified squamous cells on the mucosal surface, which is consistent with vaginal mucosal hyperplasia and shedding during normal estrus. Vaginal hyperplasia cannot be recovered, but vaginal prolapse can be recovered; Vaginal hyperplasia is related to estrus, and vaginal prolapse is related to pregnancy and delivery. Where tissue hyperplasia is serious, dogs can't mate when they leave the vulva, so they can take surgical treatment.

Three points should be paid attention to when performing biological resection: first, a catheter must be inserted before operation to identify and protect the urethra; Second, two orthopedic Kirschner wires pass through the implant after the urethral orifice to fix the vaginal wall tissue to prevent the residual vaginal wall tissue from retracting after the implant is taken out; Third, in order to reduce bleeding, in addition to ligating tourniquet before Kirschner wire, partial resection should be adopted. After hemostasis and suture, another part should be removed until it is completely removed.