Piccolo, a plastic surgeon who invented this technology, said that frog skin is rich in natural anti-infective, anti-inflammatory and anti-allergic ingredients. Covering burn wounds with frog skin can shorten the scabbing time by half. When using this method, first cut off the burned skin, then cover the wound with frog skin and replace it every two days. This method is especially suitable for treating large area burns. Sometimes a two-week treatment needs to consume 500 to 1000 pieces of frog skin.