Some people are worried about the safety of injecting botulinum toxin, and they can definitely answer that injecting botulinum toxin is safe. Its semi-lethal dose is 40IU/Kg for human and 2000IU for a patient weighing 50kg, while the dose of 0. 1 ~ 1ml liquid for cosmetic wrinkle removal is only 5 ~ 50IU, so it is very safe to inject botulinum toxin without hospitalization.