Neurosurgery in provincial hospitals can be done. At present, most surgical materials are titanium alloys, both domestic and imported. Generally, this operation is feasible 3-6 months after the condition is stable. Indications for skull defect repair: 1. The defect area is greater than 3 * 3 cm; 2. Defects affect the appearance of the skull. Contraindications: 1. Severe heart and lung failure and other important organs; 2. There are serious complications after craniotomy, such as plant survival; 3. Wound infection and cerebrospinal fluid leakage after craniotomy. See whether it meets the surgical conditions and whether there are any contraindications for surgery. The cost mainly depends on the repair materials you choose. At present, titanium plate is mainly used in clinic, and skull repair is not too difficult. Many hospitals can do it.