1. Treatment incentives (redundant prepuce, vaginitis, balanitis prepuce, gonorrhea, etc. ).
2. Improve the body's immunity.
3. Chemotherapy
(1)0.5% podophyllotoxin tincture (or 0. 15% cream) is suitable for treating genital warts with a diameter ≤ 10mm, and the clinical cure rate can reach about 90%. The total area of wart should not exceed 10cm2, and the total daily dosage should not exceed 0.5ml After taking the medicine, the local medicine will naturally dry. The side effects are mainly local irritation, including itching, burning pain, redness, erosion and necrosis. In addition, the drug has teratogenic effect and is prohibited for pregnant women.
(2) Treating condyloma acuminatum with 5% imiquimod cream, the average removal rate of warts was 56%. The advantage of this therapy is that the recurrence rate is low, about 13%. Erythema is not an indication to stop taking medicine. If erosion or injury occurs, it is necessary to stop taking drugs and return to the clinic. The doctor will treat the wound and decide whether to continue taking the medicine. The side effects are mainly local irritation, including itching, burning pain, erythema and erosion. The safety of imiquimod during pregnancy has not been determined, so it is forbidden for pregnant women.
(3) 80% ~ 90% of trichloroacetic acid or dichloroacetic acid should be handled by doctors. When in use, a small amount of liquid medicine is applied to the wart lesion, and a layer of hoarfrost is formed on the surface after drying. Attention should be paid to protecting the normal skin and mucosa around during the treatment. If there is too much liquid for external use, talcum powder, sodium bicarbonate (baking soda) or hand sanitizer can be applied to neutralize the excess unreacted acid. This medicine cannot be used for hyperkeratosis or large, multiple and large warts. Adverse reactions include local irritation, redness and erosion.
4. Cryotherapy
Low temperature liquid nitrogen (-196℃) was used to treat condyloma acuminatum by pressure freezing to promote the necrosis and shedding of wart tissue. The operation is simple and effective, and patients can tolerate it easily. This method is suitable for condyloma acuminatum with a small number and area, and it is feasible to treat it 1 ~ 2 times with an interval of one week.
5. Laser therapy
CO2 laser is usually used to treat condyloma acuminatum by cauterization. It is feasible to treat a single or a small number of multiple warts at one time, and it is feasible to treat multiple or large warts in two or three times, with an interval of one week.
6. electrocautery therapy
High-frequency electroacupuncture or electrotome was used to remove condyloma acuminatum. This therapy is suitable for condyloma acuminatum with small quantity and area.
7. aminolevulinic acid photodynamic therapy (ALA-PDT therapy)
This method can selectively kill proliferative cells, not only destroy condyloma acuminatum visible to the naked eye, but also remove subclinical damage and latent infected tissues. It has the advantages of high cure rate, low recurrence rate, few and mild adverse reactions and good patient compliance.
8. Surgical therapy
It is suitable for whole or batch excision of huge condyloma acuminatum.
9. Immunotherapy
It is not recommended to use alone, but can be used as adjuvant therapy and prevention of recurrence. Interferon can be injected intramuscularly, subcutaneously and at the base of the lesion, interleukin -2 can be injected subcutaneously or intramuscularly, and multi-muscle cells can be injected intramuscularly.