1, pudendal infection
Women usually have bad hygiene habits, often wear chemical fiber underwear, and sanitary products are not clean. They bathe in public baths and swim in baths. , leading to vaginal inflammation. If not treated in time, inflammatory secretions will infiltrate the perineum, damage the skin and mucosa for a long time, appear redness, ulcers and lesions, and gradually develop into vulvar leukoplakia.
2. Genetic factors
About 10%-30% of patients with vulvar leukoplakia are caused by heredity, and the vulvar leukoplakia caused by heredity is mainly atrophic, and the patients are mainly young girls. Clinically, for patients below 15, genetic factors should be considered first, and whether there are patients with vulvar leukoplakia in their parents' families should be asked.
3, endocrine disorders
There is a tissue-specific protein hormone called somatostatin in dermis, which can inhibit the division and growth of epidermal cells and only act on epidermis. Endocrine disorder causes the imbalance between local connective tissue hyperplasia and epidermal metabolic stimulation, leading to the appearance of vulvar leukoplakia.
4. Trauma and birth injury
Pregnant women will tear perineum in a large area during childbirth, injuring blood vessels and peripheral nerves, causing local neurovascular damage and local malnutrition, and a few women will have vulvar leukoplakia.
5, inflammatory stimulation
Causes local neurovascular damage, leading to trichomonal vaginitis, fungal vaginitis, cervical erosion and other inflammation in a few parturients, leading to an increase in leucorrhea, stimulating the vulva for a long time, and causing vulvar leukoplakia.
6. Other diseases
If women suffer from diabetes, vulvar eczema, vulvar pruritus and other diseases, once misuse of drugs leads to improper treatment, it is likely to lead to or aggravate the formation and development of vulvar leukoplakia.
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