No, the distance between Suzhou and Xuzhou is about 100 km, and the two places are relatively close. The climate, temperature, temperature difference and eating habits of the two places are similar, which will not cause too much stimulation and stress reaction to the human body, so it will not be acclimatized. Traveling from Suzhou to Xuzhou, if you are afraid of the symptoms of acclimatization, you can prepare the corresponding drugs in advance.